HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is a multi purpose buffer used in biological research.
Nucleic Acids Res. 2022 Aug 12;50(14):7938-7958.
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia
HEPES purchased from AbMole
Acta Pharm Sin B. 2022 Aug.
Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma
HEPES purchased from AbMole
Cell Commun Signal. 2022 Jul 7;20(1):102.
Circular dorsal ruffles disturb the growth factor-induced PI3K-AKT pathway in hepatocellular carcinoma Hep3B cells
HEPES purchased from AbMole
Nat Commun. 2021 Jun 23;12(1):3896.
Single cell derived mRNA signals across human kidney tumors
HEPES purchased from AbMole
EMBO Mol Med. 2021 Jul 7;13(7):e13067.
Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis
HEPES purchased from AbMole
Adv Healthc Mater. 2021 Aug;10(16):e2100821.
Extracellular Matrix Stiffness Regulates DNA Methylation by PKCα-Dependent Nuclear Transport of DNMT3L
HEPES purchased from AbMole
Cell Death Dis. 2021 Feb 15;12(2):179.
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors
HEPES purchased from AbMole
Cells. 2021 Feb 18;10(2):430.
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
HEPES purchased from AbMole
Cell Stem Cell. 2020 Nov 5;27(5):840-851.e6.
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
HEPES purchased from AbMole
Nat Commun. 2020 Aug 27;11(1):4279.
Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer
HEPES purchased from AbMole
Environ Health Perspect. 2020 Jun;128(6):67008.
Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation
HEPES purchased from AbMole
Sci Rep. 2020 Jul 31;10(1):12991.
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis
HEPES purchased from AbMole
J Virol. 2020 Feb 14;94(5):e01791-19.
Targeting Kaposi's Sarcoma-Associated Herpesvirus ORF21 Tyrosine Kinase and Viral Lytic Reactivation by Tyrosine Kinase Inhibitors Approved for Clinical Use
HEPES purchased from AbMole
NAS. 2020 Jun.
Multiscale activity imaging in mammary gland reveals how oxytocin enables lactation
HEPES purchased from AbMole
Molecular Weight | 238.3 |
Formula | C8H18N2O4S |
CAS Number | 7365-45-9 |
Solubility (25°C) | Water ≥ 200 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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Collagen Type I, Bovine (300 kDa)
Bovine Collagen I is a purified stromal extracellular matrix protein that can promtes cell adhesion for cell and tissue culture. It may also be used to supplement customized coatings, hydrogels, bioinks, or medium formulations for cell culture. |
Collagen Type I, Bovine
Bovine Collagen I is a purified stromal extracellular matrix protein that can promtes cell adhesion for cell and tissue culture. It may also be used to supplement customized coatings, hydrogels, bioinks, or medium formulations for cell culture. |
O4I3
O4I3 is a potent and selective inhibitor of the KDM5A (JARID1A) isoform of H3K4 demethylase, with an IC50 value of 0.15 nM.O4I3 effectively induces OCT4 expression and enhances OSKM-induced pluripotent stem cell reprogramming efficiency (50 nM) of human primary fibroblasts by preventing KDM5A from interfering with the enrichment of H3K4Me3 on the OCT4 promoter. iPSC) reprogramming efficiency (50 nM). |
Glycogen (from oyster)
Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. Oyster glycogen has been used to induce inflammation and to promote extravasation of granulocytes and neutrophils in animal models after intraperitoneal injection. Glycogen also acts as a vascular permeability probe. |
L-Alanyl-L-glutamine, for cell culture
L-Alanyl-L-glutamine, for cell culture is cell culture grade proglutide, a stabilized form of L-glutamine. |
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