Triton X-100 is a nonionic, non-denaturing detergent suitable for solubilization, isolation and purification of membrane protein complexes. It is chemically indistinguishable from Nonidet P-40.
Front Pharmacol. 2021 Feb 16;12:625074.
Saikosaponin D Rescues Deficits in Sexual Behavior and Ameliorates Neurological Dysfunction in Mice Exposed to Chronic Mild Stress
Triton X-100 purchased from AbMole
Nanoscale. 2021 May 13;13(18):8614-8622.
Ordered inverse-opal scaffold based on bionic transpiration to create a biomimetic spine
Triton X-100 purchased from AbMole
Neural Plast. 2021 Apr 19;2021:6680192.
The Wnt/ β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model
Triton X-100 purchased from AbMole
Int J Chron Obstruct Pulmon Dis. 2021 Jun 4;16:1661-1675.
Histone Deacetylase 2 Suppresses Skeletal Muscle Atrophy and Senescence via NF-κB Signaling Pathway in Cigarette Smoke-Induced Mice with Emphysema
Triton X-100 purchased from AbMole
Front Pharmacol. 2021 May 17;12:589273.
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
Triton X-100 purchased from AbMole
DNA Cell Biol. 2021 Jul;40(7):895-905.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5
Triton X-100 purchased from AbMole
Nat Commun. 2020 Sep 15;11(1):4629.
Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity
Triton X-100 purchased from AbMole
Front Immunol. 2020 Oct 14;11:571959.
Threonyl-tRNA Synthetase Promotes T Helper Type 1 Cell Responses by Inducing Dendritic Cell Maturation and IL-12 Production via an NF-κB Pathway
Triton X-100 purchased from AbMole
Exp Cell Res. 2020 Nov 1;396(1):112237.
LRTM1 promotes the differentiation of myoblast cells by negatively regulating the FGFR1 signaling pathway
Triton X-100 purchased from AbMole
2020 Sep.
Developing a model to assess the contribution of cytokeratin 19-expressing cells during multipotent stromal cell-induced islet regeneration
Triton X-100 purchased from AbMole
Nat Biomed Eng. 2020 Sep;4(9):875-888.
Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies
Triton X-100 purchased from AbMole
Front Oncol. 2020 May 21;10:667.
Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1
Triton X-100 purchased from AbMole
Drug Chem Toxicol. 2016 Oct;39(4):392-9.
Effects of 2,4-dichlorophenoxyacetic acid on the ventral prostate of rats during the peri-pubertal, pubertal and adult stage
Triton X-100 purchased from AbMole
Neurochem Res. 2020 Sep;45(9):2020-2031.
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats
Triton X-100 purchased from AbMole
Environ Health Perspect. 2020 Jun;128(6):67008.
Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation
Triton X-100 purchased from AbMole
Life Sci. 2020 Sep 15;257:118021.
TRIB3 destabilizes tumor suppressor PPARα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia
Triton X-100 purchased from AbMole
Anat Rec (Hoboken). 2020 Jan 21.
Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation
Triton X-100 purchased from AbMole
Sci Adv. 2020 Jul 10;6(28):eaba7260.
A basal-bolus insulin regimen integrated microneedle patch for intraday postprandial glucose control
Triton X-100 purchased from AbMole
Aging (Albany NY). 2020 Jun 9;12(11):11025-11041.
LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis
Triton X-100 purchased from AbMole
PLoS Pathog. 2020 Apr 13;16(4):e1008498.
Intestinal Restriction of Salmonella Typhimurium Requires caspase-1 and caspase-11 Epithelial Intrinsic Inflammasomes
Triton X-100 purchased from AbMole
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
Molecular Weight | |
Formula | C14H22O.n(C2H4O) |
CAS Number | 9002-93-1 |
Purity | for molecular biology |
Solubility | Soluble in water |
Storage | room temperature |
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