Triton x-100 is a nonionic, non-denaturing detergent suitable for solubilization, isolation and purification of membrane protein complexes.It is chemically indistinguishable from Nonidet P-40.
PLoS Pathog. 2020 Apr 13;16(4):e1008498.
Intestinal Restriction of Salmonella Typhimurium Requires caspase-1 and caspase-11 Epithelial Intrinsic Inflammasomes
Triton x-100 purchased from AbMole
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Purity||for molecular biology|
|Solubility||Soluble in water|
Sorption and transport studies of cetyl trimethylammonium bromide (CTAB) and Triton X-100 in clayey soil.
Harendra S, et al. J Environ Sci. 2013 Mar 1;25(3):576-84. PMID: 23923432.
Micellar-enhanced ultrafiltration of copper ions using sodium dodecyl sulfate and its mixture with Brij 35, Tween 80 and Triton X-100.
Zhao B, et al. Water Sci Technol. 2013;67(10):2154-9. PMID: 23676382.
6-Methoxynicotinamide is a potent Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively.
3-Bromopyruvic acid is a hexokinase II inhibitor, which is an effective antitumor agent on the hepatoma cells.
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
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