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Estradiol

Cat. No. M5625
Estradiol Structure
Synonym:

β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol

Size Price Availability Quantity
500mg USD 64 In stock
1g USD 80 In stock
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Quality Control
Biological Activity

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 272.38
Formula C18H24O2
CAS Number 50-28-2
Purity 99.40%
Solubility 54 mg/mL in DMSO
Storage at -20°C
References

Effects of preovulatory estradiol on embryo survival and pregnancy establishment in beef cows.
Madsen CA, et al. Anim Reprod Sci. 2015 Jul;158:96-103. PMID: 26022231.

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Keywords: Estradiol, β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol supplier, Estrogen Receptor, inhibitors

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