Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharide is a highly immunogenic antigen which can enhance immune responses. This product is derived from Escherichia coli O55:B5. Its potency is more than 500,000 EU/mg.
Crit Care. 2024 Jan;28(1):36.
The protective effect of apolipoprotein H in paediatric sepsis
Lipopolysaccharides purchased from AbMole
J Ethnopharmacol. 2024 Jan 30;319(Pt 3):117337.
Essential Oil from Ligusticum Chuanxiong Hort. Alleviates Lipopolysaccharide-Induced Neuroinflammation: Integrating Network Pharmacology and Molecular
Lipopolysaccharides purchased from AbMole
JPI. 2024 Jan-Feb;67(1):p 47-56.
Fatty Acid Binding Protein-4 Silencing Inhibits Ferroptosis to Alleviate Lipopolysaccharide-induced Injury of Renal Tubular Epithelial Cells by Blocking Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling
Lipopolysaccharides purchased from AbMole
EBioMedicine. 2023 Dec 6;99:104904.
Multi-omics analyses reveal bacteria and catalase associated with keloid disease
Lipopolysaccharides purchased from AbMole
Food Chemistry. 2023 Dec 15;136858.
Thiol-modified hyaluronic acid improves the physical stability of curcumin-zein nanoparticles by forming disulfide bonds with zein
Lipopolysaccharides purchased from AbMole
Biomed Pharmacother. 2023 May;161:114575.
Targeting the TNF-α–TNFR interaction with EGCG to block NF-κB signaling in human synovial fibroblasts
Lipopolysaccharides purchased from AbMole
Front Immunol. 2022 Aug 15;13:914381.
YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials
Lipopolysaccharides purchased from AbMole
Oxid Med Cell Longev. 2022 Apr 16;2022:4505513.
Nrf2-Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute-on-Chronic Liver Failure
Lipopolysaccharides purchased from AbMole
J Funct Foods. 2022 Aug;Volume 95, 105191.
Royal jelly attenuates LPS-induced immune dysfunction of dendritic cells via Nrf2/HO-1 axis
Lipopolysaccharides purchased from AbMole
Mol Med Rep. 2022 Jul;26(1):220.
Tranilast attenuates lipopolysaccharide‑induced lung injury via the CXCR4/JAK2/STAT3 signaling pathway
Lipopolysaccharides purchased from AbMole
Can Respir J. 2022 Jul 31;2022:8433960.
Dexmedetomidine Attenuates LPS-Stimulated Alveolar Type II Cells' Injury through Upregulation of miR-140-3p and Partial Suppression of PD-L1 Involving Inactivating JNK-Bnip3 Pathway
Lipopolysaccharides purchased from AbMole
Mar Drυgs. 2020 Oct 28;18(11):538.
Immunostimulatory Effects of Polysaccharides from Spirulina platensis In Vivo and Vitro and Their Activation Mechanism on RAW246.7 Macrophages
Lipopolysaccharides purchased from AbMole
Solubility (25°C) | Water ≥ 5 mg/mL |
Storage | 2-8°C, protect from light, sealed |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat
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PLP (139-151)
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G6PI 325-339 (human)
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Heparin sodium salt (MW 15kDa)
Heparin sodium salt (MW 15kDa) is a heparin polymer with a molecular weight of 15kDa.Heparin sodium salt is an anticoagulant that reversibly binds to antithrombin III (ATIII), thereby accelerating the rate of inactivation of Thrombin factor IIa and factor Xa by ATIII. Heparin sodium salt is used for blood collection and plasma preparation in experimental animals and for the construction of parenteral nutrition models in mice. |
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