Streptomycin Sulfate is the sulfate salt form of streptomycin, an aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial property. Streptomycin sulfate binds to the S12 protein of the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis, consequently leading to bacterial cell death. Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
J Med Chem. 2023 Dec;17138–17154.
All-Hydrocarbon Stapled Peptide Multifunctional Agonists at Opioid and Neuropeptide FF Receptors: Highly Potent, Long-Lasting Brain Permeant Analgesics with Diminished Side Effects
Streptomycin sulfate purchased from AbMole
J Inflamm Res. 2021 Mar 17;14:917-928.
Stable Cells with NF-κB-ZsGreen Fused Genes Created by TALEN Editing and Homology Directed Repair for Screening Anti-inflammation Drugs
Streptomycin sulfate purchased from AbMole
Lipids Health Dis. 2021 Apr 26;20(1):40.
Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease
Streptomycin sulfate purchased from AbMole
Sci Adv. 2020 Jul 10;6(28):eaba7260.
A basal-bolus insulin regimen integrated microneedle patch for intraday postprandial glucose control
Streptomycin sulfate purchased from AbMole
J Exp Clin Cancer Res. 2020 May 24;39(1):93.
TFEB-NF-κB Inflammatory Signaling Axis: A Novel Therapeutic Pathway of Dihydrotanshinone I in Doxorubicin-Induced Cardiotoxicity
Streptomycin sulfate purchased from AbMole
Br J Cancer. 2020 May;122(11):1673-1685.
CSN6-TRIM21 Axis Instigates Cancer Stemness During Tumorigenesis
Streptomycin sulfate purchased from AbMole
Cell Commun Signal. 2020 Feb 17;18(1):27.
mTOR May Interact With PARP-1 to Regulate Visible Light-Induced Parthanatos in Photoreceptors
Streptomycin sulfate purchased from AbMole
Sci Rep. 2020 Jul 31;10(1):12991.
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis
Streptomycin sulfate purchased from AbMole
Fish Shellfish Immunol. 2020 Jul;102:480-488.
Target of rapamycin signaling inhibits autophagy in sea cucumber Apostichopus japonicus
Streptomycin sulfate purchased from AbMole
Pharmaceuticals (Basel). 2020 Mar 30;13(4):59.
In Vitro Antibacterial and Antiproliferative Potential of Echinops lanceolatus Mattf. (Asteraceae) and Identification of Potential Bioactive Compounds
Streptomycin sulfate purchased from AbMole
Mar Drυgs. 2020 Aug 17;18(8):429.
Comparison of Physicochemical Characteristics and Macrophage Immunostimulatory Activities of Polysaccharides from Chlamys farreri
Streptomycin sulfate purchased from AbMole
Plants (Basel). 2020 Aug 28;9(9):1111.
Plukenetia huayllabambana Fruits: Analysis of Bioactive Compounds, Antibacterial Activity and Relative Action Mechanisms
Streptomycin sulfate purchased from AbMole
J Steroid Biochem Mol Biol. 2013 Nov;138:54-62.
Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibroblasts
Streptomycin sulfate purchased from AbMole
Molecular Weight | 581.57 |
Formula | C21H39N7O12 |
CAS Number | 3810-74-0 |
Solubility (25°C) | Water 86 mg/mL |
Storage | -20°C, protect from light, sealed |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
Related Antibiotic Products |
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Kendomycin
Kendomycin is a polyketide antibiotic with significant antibacterial activity and tumor cytotoxicity. At low concentrations (MIC: 5 μg/mL), Kendomycin inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA) strain COL. In addition, Kendomycin is an endothelin receptor antagonist and calcitonin receptor agonist. |
Ceftobiprole
Ceftobiprole is a broad-spectrum cephalosporin with rapid bactericidal activity against Gram-positive bacteria such as Staphylococcus aureus, including methicillin-resistant strains (MRSA), and Gram-negative bacteria, with a MIC90 value of 2 μg/mL against MRSA. |
Showdomycin
Showdomycin is an antibiotic that is induced by IM-2 in Streptomyces. |
Quinupristin
Quinupristin is a streptogramin antibiotic. |
Buforin II
Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. |
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