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 About 12 results found for searched term "Antibiotic" (0.04 seconds)

Cat.No.  Name Target
M1831 Cyclosporine A Immunology/Inflammation
Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1
Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M2790 K252a PKC
SF 2370; Antibiotic K-252a; Antibiotic SF 2370
K252a is an inhibitor of the BDNF receptor TrkB. K-252a inhibits protein kinase with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.
M6292 Ansamitocin P 3 Microtubule
Antibiotic C 15003P3; Maytansinol butyrate
Ansamitocin P-3 is a microtubule inhibitor, it is also a macrocyclic antitumor antibiotic.
M9780 Nigericin Potassium Channel
Antibiotic K178, Antibiotic X464
Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore.
M9860 Bleomycin A5 Hydrochloride DNA/RNA Synthesis
BLEOCIN Antibiotic; Bleomycin A5 HCl
Bleomycin A5 Hydrochloride is a unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells.
M11236 Lasalocid sodium Antibiotic
Lasalocid-A sodium; Ionophore X-537A sodium; Antibiotic X-537A
Lasalocid sodium (Lasalocid-a sodium) is an antibacterial agent.
M13469 Lasalocid Antibiotic
Lasalocid-A; Ionophore X-537A; Antibiotic X-537A
Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) is an antibacterial agent and a coccidiostat, used in the feed additives
M21494 Sibofimloc Antibiotic
Antibiotic-202
Sibofimloc (CD-202) is a first-in-class, intestinal limiting and oral active inhibitor of FimH adhesion. Sibofimloc has antibacterial activity and is being developed for the study of inflammatory bowel disease (IBD).
M30025 Malonomicin Antibiotic
Antibiotic K16
Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo.
M30504 Pentachloropseudilin Myosin
Antibiotic A 15104 Y; PClP
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β.
M30588 Leucinostatin A Antifungal
Antibiotic P168
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies.
M58313 Antibiotic PF 1052 Antibiotic
PF1052
Antibiotic PF 1052 is an antibiotic from a natural product library with potent anti-inflammatory properties. Antibiotic PF 1052 has an inhibitory effect on murine neutrophil migration.



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