About 12 results found for searched term "Antibiotic" (0.04 seconds)
Cat.No. | Name | Target |
---|---|---|
M1831 | Cyclosporine A | Immunology/Inflammation |
Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1 | ||
Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. | ||
M2790 | K252a | PKC |
SF 2370; Antibiotic K-252a; Antibiotic SF 2370 | ||
K252a is an inhibitor of the BDNF receptor TrkB. K-252a inhibits protein kinase with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene. | ||
M6292 | Ansamitocin P 3 | Microtubule |
Antibiotic C 15003P3; Maytansinol butyrate | ||
Ansamitocin P-3 is a microtubule inhibitor, it is also a macrocyclic antitumor antibiotic. | ||
M9780 | Nigericin | Potassium Channel |
Antibiotic K178, Antibiotic X464 | ||
Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore. | ||
M9860 | Bleomycin A5 Hydrochloride | DNA/RNA Synthesis |
BLEOCIN Antibiotic; Bleomycin A5 HCl | ||
Bleomycin A5 Hydrochloride is a unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. | ||
M11236 | Lasalocid sodium | Antibiotic |
Lasalocid-A sodium; Ionophore X-537A sodium; Antibiotic X-537A | ||
Lasalocid sodium (Lasalocid-a sodium) is an antibacterial agent. | ||
M13469 | Lasalocid | Antibiotic |
Lasalocid-A; Ionophore X-537A; Antibiotic X-537A | ||
Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) is an antibacterial agent and a coccidiostat, used in the feed additives | ||
M21494 | Sibofimloc | Antibiotic |
Antibiotic-202 | ||
Sibofimloc (CD-202) is a first-in-class, intestinal limiting and oral active inhibitor of FimH adhesion. Sibofimloc has antibacterial activity and is being developed for the study of inflammatory bowel disease (IBD). | ||
M30025 | Malonomicin | Antibiotic |
Antibiotic K16 | ||
Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo. | ||
M30504 | Pentachloropseudilin | Myosin |
Antibiotic A 15104 Y; PClP | ||
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β. | ||
M30588 | Leucinostatin A | Antifungal |
Antibiotic P168 | ||
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies. | ||
M58313 | Antibiotic PF 1052 | Antibiotic |
PF1052 | ||
Antibiotic PF 1052 is an antibiotic from a natural product library with potent anti-inflammatory properties. Antibiotic PF 1052 has an inhibitory effect on murine neutrophil migration. |
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