All AbMole products are for research use only, cannot be used for human consumption.
K252a is an inhibitor of the BDNF receptor TrkB. K-252a inhibits protein kinase with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.
Tianjin Medical Journal. 2023;51(4):387-391.
Study on the mechanism of glial maturation factor-β induced inflammatory response of retinal Müller cells in diabetes rats
K252a purchased from AbMole
| Molecular Weight | 467.47 |
| Formula | C27H21N3O5 |
| CAS Number | 99533-80-9 |
| Solubility (25°C) | DMSO 50 mg/mL (Need ultrasonic and warming) |
| Storage | -20°C |
[4] Alessandro Morotti, et al. K252a inhibits the oncogenic properties of Met, the HGF receptor
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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