About 1 result found for searched term "99533-80-9" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2790 | K252a | PKC |
| SF 2370; Antibiotic K-252a | ||
| K252a is an inhibitor of the BDNF receptor TrkB. K-252a inhibits protein kinase with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene. | ||
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