Cat.No. | Name | Information |
---|---|---|
M58683 | Methoctramine tetrahydrochloride | Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. |
M58682 | Flurandrenolide | Fludroxycortide is a synthetic topical steroid with anti-inflammatory effects and has potential for research of skin irritation. |
M58680 | Traumatic Acid | Traumatic acid (Trans-2-dodecenedioic acid) is the product of a biosynthetic pathway from a physiological role of alpha-ketol fatty acids in plant lipid hydroperoxide lyase metabolism. Traumatic acid (Trans-2-dodecenedioic acid) is also used in would healing as it stimulates cell division to form a protective callus around the wound site. |
M58679 | T-00127-HEV1 | T-00127-HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM. |
M58678 | MORF-627 | MORF-627 is a selective, orally active inhibitor for integrin αvβ6 with an IC50 of 9.2 nM (measuring by human serum ligand binding assay). MORF-627 inhibits αvβ6-mediated TGF-β1 activation with an IC50 of 2.63 nM, inhibits SMAD2/3 phosphorylation with an IC50 of 8.3 nM. |
M58677 | TMTP1 Peptide | TMTP1 is a 5-amino acid peptide NVVRQ, it can be used for the labeling of malignant in situ and metastatic lesions, and even micro-metastases. TMTP1 specifically bound to the cells of a series of hematological malignancies, including HL60, k562, Jurkat, Raji, El-4 and chronic myeloid leukemia primary cells but not to bone marrow mononuclear cells from healthy subjects. TMTP1, as a novel tumor-homing peptide, can serve as a marker for primary malignant and metastatic lesions. |
M58676 | c-di-AMP disodium | c-di-AMP disodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP disodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. |
M58675 | 25-OH Vitamin D3/BSA | 25-OH Vitamin D3/BSA is an antigen-adjuvant coupling of 25-OH Vitamin D3 conjugated to bovine serum albumin (BSA). |
M58674 | Recombinant Human LAG-3 Protein (HEK293, C-hFc) | Lymphocyte activation gene 3 protein (LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. It can lead to increased antigen-specific T-cell responses in vivo. |
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