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c-di-AMP disodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP disodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP disodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.
Molecular Weight | 702.38 |
Formula | C20H22N10Na2O12P2 |
CAS Number | 2734909-87-4 |
Solubility (25°C) | DMSO 120 mg/mL Water 50 mg/mL |
Storage | Store at ≤ -20°C, protect from light, sealed |
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