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c-di-AMP disodium

Cat. No. M58676

All AbMole products are for research use only, cannot be used for human consumption.

c-di-AMP disodium Structure
Synonym:

Cyclic diadenylate disodium; Cyclic-di-AMP disodium

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Quality Control & Documentation
Biological Activity

c-di-AMP disodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP disodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP disodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Chemical Information
Molecular Weight 702.38
Formula C20H22N10Na2O12P2
CAS Number 2734909-87-4
Solubility (25°C) DMSO 120 mg/mL
Water 50 mg/mL
Storage Store at ≤ -20°C, protect from light, sealed
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  Catalog
Abmole Inhibitor Catalog




Keywords: c-di-AMP disodium, Cyclic diadenylate disodium; Cyclic-di-AMP disodium supplier, STING, inhibitors, activators

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