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STING Stimulator of Interferon Genes

Cat.No.  Name Information
M10459 MSA-2 MSA-2 is an orally available non-nucleotide STING agonist with antitumor activity. MSA-2 shows EC50 values of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
M21652 SN-001 SN-001 is a STING inhibitor with an IC50 of 3.82 μM. SN-001 targets the cyclic dinucleotide binding pocket of human STING.
M14125 STING-IN-2 STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research.
M14121 Cyclic-di-GMP Cyclic-di-GMP (c-di-GMP) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.
M14120 cGAMP disodium cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA.
M14119 cGAMP diammonium cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA.
M11332 diABZI STING agonist-1 trihydrochloride DiABZI STING Agonist-1 (Trihydrochloride) is a selective agonist of interferon gene-stimulated receptor (STING), with EC50 scores of 130 nM and 186 nM in mice and humans, respectively.
M10766 ADU-S100 disodium salt ADU-S100 disodium salt (MIW815 disodium salt) is an activator (STING) of interferon gene stimulators with potent antitumor and immune activity.
M10765 ADU-S100 ammonium salt ADU-S100 ammonium salt (MIW815 ammonium salt) is an activator (STING) of interferon gene stimulators with potent antitumor and immune activity.
M10299 c-di-AMP c-di-AMP (Cyclic diadenylate) is a STING agonist, it binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.
M10126 H-151 H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
M10125 C-178 C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation.
M9923 SR-717 SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.
M9893 C-176 C-176 is a potent small-molecule inhibitor of STING.
M9729 diABZI STING agonist 1 (compound 3) diABZI STING agonist-1 (compound 3) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
M9453 3′3′-cGAMP 3',3'-cGAMP is an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. 3',3'-cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators.
M9084 STING-Inducer-1 STING-Inducer-1 (ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes).
M6739 G10 G10 is a activator of STING-dependent signaling.
M1999 Vadimezan (DMXAA) Vadimezan (DMXAA; ASA-404) acts as a tumor vascular disrupting agent (tumor-VDA), is also a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines.
M42060 STING agonist-30 STING agonist-30 is a potent STING agonist.




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