| Cat.No. | Name | Information |
|---|---|---|
| M10459 | MSA-2 | MSA-2 is an orally available non-nucleotide STING agonist with antitumor activity. MSA-2 shows EC50 values of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. |
| M9923 | SR-717 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. |
| M9893 | C-176 | C-176 is a potent, selective and blood-brain barrier permeable inhibitor of STING. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING. |
| M1999 | Vadimezan (DMXAA) | Vadimezan (DMXAA; ASA-404) acts as a tumor vascular disrupting agent (tumor-VDA), is also a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. |
| M56403 | IACS-8779 | IACS-8779 is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. |
| M56402 | IACS-8803 | IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy. |
| M56401 | STING-IN-6 | STING-IN-6 is a potent STING inhibitor with a pIC50 of 8.9. |
| M56400 | MSA-2 dimer | MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. |
| M56399 | 2',3'-cGAMP-C2-PPA | 2’,3’-cGAMP-C2-PPA is a cyclic dinucleotide interferon gene-stimulating protein (STING) agonist. |
| M56398 | IACS-8803 disodium | IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. |
| M56397 | IACS-8779 disodium | IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. |
| M42060 | STING agonist-30 | STING agonist-30 is a potent STING agonist. |
| M42059 | F-CRI1 | F-CRI1 is a potent STING agonist with a Kd value of 40.62 nM. |
| M42058 | STING agonist-31 | STING agonist-31 is a STING agonist, with EC50 values of 0.24 and 39.51 μM for h-STING and m-STING. |
| M42057 | BI 7446 | BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. |
| M42056 | STING agonist-8 dihydrochloride | STING agonist-8 dihydrochloride is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells. |
| M40559 | MK-2118 | MK-2118 is a STING1 agonist that can be used in studies related to lymphoma. |
| M40558 | GSK3745417 | GSK3745417 is a STING1 agonist that can be used in tumor-related studies. |
| M40557 | SNX281 | SNX281 is a STING1 agonist that can be used in studies related to solid tumors. |
| M40556 | IMSA101 | IMSA101 is a STING1 agonist that can be used in studies related to solid tumors. |
| M40555 | BI1387446 | BI1387446 is a STING1 agonist that can be used in studies related to solid tumors. |
| M40554 | SB11285 | SB11285 is a STING1 stimulator that can be used in melanoma related studies. |
| M29813 | PROTAC STING Degrader-1 | PROTAC STING Degrader-1 (Compound SP23) is a STING PROTAC degrader with a DC50 of 3.2 μM. PROTAC STING Degrader-1 shwos anti-inflammatory activity. |
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