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G10 is a activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. Exhibits no effect on NF-κB signaling. Blocks viral replication in vitro.
| Molecular Weight | 430.88 |
| Formula | C21H16ClFN2O3S |
| CAS Number | 702662-50-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 43.09 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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