About 30 results found for searched term "G10" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1733 | TG101348 | JAK |
| Fedratinib; SAR302503 | ||
| TG101348 is a selective small-molecule Janus kinase 2 (JAK2) inhibitor with IC50 of 3 nM. | ||
| M1886 | TG100-115 | PI3K |
| TG100-115 is a selective PI3K γ/δ inhibitor with IC50 values of 83 and 235 nM respectively. | ||
| M1887 | TG101209 | JAK |
| TG101209 is a novel small molecule, ATP-competitive JAK2-selective kinase inhibitor (IC50 = 6 nM). | ||
| M2182 | RG108 | DNA Methyltransferase |
| N-Phthalyl-L-tryptophan | ||
| RG108 is a novel small-molecule inhibitors of DNA methyltransferases with IC50 of 115 nM. | ||
| M3063 | TG100713 | PI3K |
| TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively. | ||
| M6739 | G10 | STING |
| G10 is a activator of STING-dependent signaling. | ||
| M7372 | TC-G 1003 | Somatostatin Receptor |
| TCG1003 | ||
| TC-G 1003 is a high affinity somatostatin sst2 receptor agonist. | ||
| M8275 | LG100268 | Others |
| LG100268 (LG268) is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. | ||
| M10764 | Acoramidis hydrochloride | Transthyretin (TTR) |
| AG10 hydrochloride | ||
| Acoramidis (AG10) hydrochloride is an orally active, selective stabilizer of the thyroxine transporter (TTR (transthyretin)) that is effective against both wild-type and V1221 mutant types. Acoramidis (AG10) hydrochloride can be used for the study of transthyroxine amyloidosis. | ||
| M10775 | Acoramidis | Transthyretin (TTR) |
| AG10 | ||
| Acoramidis (AG10) is an orally active, selective stabilizer of the thyroxine transporter (TTR) that is effective against both wild-type and V1221 mutant types. | ||
| M21500 | Polmacoxib | COX |
| CG100649 | ||
| Polmacoxib (CG100649) is a first-in-class, orally active non-steroidal anti-inflammatory compound (NSAID) that acts as a dual inhibitor. It inhibited COX-2 (IC50 ~ 0.1 μg/ml) and carbonic anhydrase. | ||
| M24687 | Asunercept | Fusion Proteins |
| APG101; CAN008 | ||
| Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD). | ||
| M25560 | HG106 | ROS |
| HG106 is a potent SLC7A11 inhibitor, it can enhance ROS generation, ER stress, and lead to ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD). | ||
| M31338 | ANG1005 | Others |
| Paclitaxel trevatide | ||
| ANG1005 is a paclitaxel derivative as well as a peptide-coupled compound (PDC) consisting of three paclitaxel and Angiopep-2 covalently linked. In addition, ANG1005 is a modulator of LDLR and an inhibitor of mitosis and microtubule proteins. | ||
| M51343 | [Des-Arg10]-HOE I40 | Others |
| [Des-Arg10]-HOE I40 is a biological active peptide. | ||
| M53077 | PG106 | Melanocortin Receptor |
| PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor. | ||
| M56788 | LG101506 | RAR/RXR |
| LG101506 is a selective and orally active RXR modulator with a Ki of 2.7 nM for RXRα. | ||
| M56786 | LG100754 | RAR/RXR |
| LG100754 (UVI 2112) is a RXR dimers modulater. | ||
| M59602 | RNF167 Human Pre-designed siRNA Set | siRNA |
| ring finger protein 167 | ||
| Human RNF167 Pre-designed siRNA Set contains three designed siRNAs for RNF167 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 26001 | ||
| M62146 | PGK1 Human Pre-designed siRNA Set | siRNA |
| phosphoglycerate kinase 1 | ||
| Human PGK1 Pre-designed siRNA Set contains three designed siRNAs for PGK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 5230 | ||
| M62383 | ATG101 Human Pre-designed siRNA Set | siRNA |
| autophagy related 101 | ||
| Human ATG101 Pre-designed siRNA Set contains three designed siRNAs for ATG101 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 60673 | ||
| M62600 | slc1a1 Mouse Pre-designed siRNA Set | siRNA |
| solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | ||
| Mouse slc1a1 Pre-designed siRNA Set contains three designed siRNAs for slc1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 20510 | ||
| M62811 | TSG101 Human Pre-designed siRNA Set | siRNA |
| tumor susceptibility 101 | ||
| Human TSG101 Pre-designed siRNA Set contains three designed siRNAs for TSG101 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7251 | ||
| M63265 | PSMB8 Human Pre-designed siRNA Set | siRNA |
| proteasome 20S subunit beta 8 | ||
| Human PSMB8 Pre-designed siRNA Set contains three designed siRNAs for PSMB8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 5696 | ||
| M63278 | IFIT2 Human Pre-designed siRNA Set | siRNA |
| interferon induced protein with tetratricopeptide repeats 2 | ||
| Human IFIT2 Pre-designed siRNA Set contains three designed siRNAs for IFIT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 3433 | ||
| M63318 | MFGE8 Human Pre-designed siRNA Set | siRNA |
| milk fat globule EGF and factor V/VIII domain containing | ||
| Human MFGE8 Pre-designed siRNA Set contains three designed siRNAs for MFGE8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 4240 | ||
| M63420 | ENC1 Human Pre-designed siRNA Set | siRNA |
| ectodermal-neural cortex 1 | ||
| Human ENC1 Pre-designed siRNA Set contains three designed siRNAs for ENC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 8507 | ||
| M63931 | GSDMD Human Pre-designed siRNA Set | siRNA |
| gasdermin D | ||
| Human GSDMD Pre-designed siRNA Set contains three designed siRNAs for GSDMD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 79792 | ||
| M65094 | ATG10 Human Pre-designed siRNA Set | siRNA |
| autophagy related 10 | ||
| Human ATG10 Pre-designed siRNA Set contains three designed siRNAs for ATG10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 83734 | ||
| M65260 | Caprin1 Mouse Pre-designed siRNA Set | siRNA |
| cell cycle associated protein 1 | ||
| Mouse Caprin1 Pre-designed siRNA Set contains three designed siRNAs for Caprin1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 53872 | ||
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