| Cat.No. | Name | Information |
|---|---|---|
| M59112 | BMS-984923 | BMS-984923 is a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling. |
| M59111 | Recombinant Human S100P (E. coli, N-6His) | Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca, S100P also binds Zn and Mg, and may play a role in the etiology of prostate cancer. |
| M59110 | Myoglobin (from equine skeletal muscle) | Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO2, MbO2 is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells. |
| M59109 | Hemoglobin (from bovine blood) | Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. |
| M59108 | Pepsin (porcine stomach mucose) | Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin is a commonly used digestive enzyme for immunohistochemical procedures. |
| M59106 | 3-Fucosyllactose | 3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function. |
| M59105 | Ulocuplumab-MMAE | Ulocuplumab-MMAE is an antibody-drug conjugate (ADC). |
| M59104 | NEO214 | NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram and perillyl alcohol. NEO214 has anti-cancer activity and blood-brain barrier (BBB) permeability. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. |
| M59103 | 123B9 | 123B9 is a tumor-homing agent, it is also a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. |
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