| Cat.No. | Name | Information |
|---|---|---|
| M58633 | PCL-PEG-MAL | PCL-PEG-MAL is an amphiphilic block copolymer consisting of polycaprolactone (PCL), polyethylene glycol (PEG) and maleimide (MAL) functional groups. PCL-PEG-MAL is used in targeted delivery systems, surface modification of nanomaterials, functionalisation of biomaterials and biosensing technologies for specific chemical linkages or biomolecular immobilisation. |
| M58630 | JPE-1375 | JPE-1375 is a complement C5a receptor 1 (C5aR1) antagonist. JPE-1375 effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice. |
| M58628 | Recombinant Mouse Progranulin Protein (HEK293, C-His) | Progranulin (PGRN) proteins regulate lysosomal function, affecting protein transport, enzymatic activity, and acidification. It degrades mature cathepsin D via cathepsin B. The precursor protein, progranulin, is also called Proepithelin and PC cell-derived growth factor. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. |
| M58627 | Recombinant Human FGF-8b Protein (E. coli) | Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect. |
| M58620 | Amylin amide, human TFA | Amylin amide, human TFA is a 37-amino acid polypeptide, it is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin amide, human TFA inhibits glucagon secretion, delays gastric emptying. |
| M58618 | Recombinant Rat GDNF Protein (Baculovirus-Insect, N-His) | GDNF is an important member of the GDNF family of ligands. GDNF plays a key role in the promotion of the survival of dopaminergic neurons. GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein also promotes the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. GDNF also regulates kidney development and spermatogenesis, and it affects alcohol consumption. |
| M58611 | Recombinant Human SOD1 Protein (E. coli, N-6His) | SOD1 binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. SOD1 neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. The enzyme protects the cell against dangerous levels of superoxide. |
| M58610 | Recombinant Human SOD2 (HEK293, C-6His) | SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. |
| M58609 | Dencatistat | Dencatistat (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC50 value of ≤ 0.1 μM. |
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