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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M19993 Recombinant Human B4GALT1 (HEK293, C-6His) Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291.
M19986 Recombinant Human CXCL6 (HEK293, C-6His) Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162.
M19981 Recombinant Rat MIP-3 α/CCL20 (HEK 293) Macrophage inflammatory protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine in the CC chemokine family. Accession P97884 - # 1.
M19980 Recombinant Mouse MIP-3α/CCL20 (E. coli) Macrophage Inflammatory Protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. Determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells, the biologically active is in a concentration range of 0.1-10.0 ng/ml.
M19977 Recombinant Human PRCP (HEK293, C-6His) Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. Accession: P42785.
M15109 Recombinant Mouse IL-10 (CHO) Recombinant Mouse IL-10 (CHO) belongs to the IL-10 family and shares more than 80% sequence homology with the Epstein-Barr Virus protein BCRFI. Measured in a cell proliferation assay using MC/9 cells, the ED50 is < 0.2 ng/ml.
M15098 Recombinant Human PCSK9 (HEK293,C-6His) Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. Accession #: Q8NBP7.
M15095 Recombinant Mouse RANKL (HEK293, N-6His) Recombinant Mouse RANKL/TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
M15093 Recombinant Human EpCAM/Trop1 (Expi293, C-His) Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain.
M15087 Recombinant Human Wnt3a (E. coli) Recombinant human WnT-3A protein was produced by Escherichia coli expression system. The DNA sequence encoding human WNT3A (Ser19-Lys352) was fused to the His tag. Accession # P56704.
M15086 Recombinant Human TGF-beta 1 (HEK293) Recombinant human transforming growth factor β 1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The ED50 for this effect is 4-40 pg/ml.
M15085 Recombinant Mouse SHH (C25II, E.coli) Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body.
M15084 Recombinant Mouse Sonic Hedgehog/Shh (E.coli) Recombinant mouse Sonic Hedgehog gene was prepared by escherichia coli expression system and the target gene encoding Cys25-Gly198 was expressed. Accession # : Q62226.
M15083 Recombinant Human Sonic Hedgehog/Shh (E.coli, C24II) Recombinant human Sonic Hedgehog gene was produced by escherichia coli expression system and the target gene encoding CYS24-Gly197 (C24II) was expressed.
M15081 Recombinant Human Prolactin/PRL (E.coli) Recombinant human prolactin was prepared by escherichia coli expression system and the target gene encoding Leu29-Cys227 was expressed. Accession # : P01236.
M15080 Recombinant Human OSM (E.coli, N-6His) Recombinant human Oncostatin M is produced by escherichia coli expression system, and the target gene encoding AlA26-ARG221 was expressed at the N-terminal with 6His marker. Measured by the dose-dependent stimulation of TF-1 cells. The ED50 for this effect is 0.2-1 ng/ml.
M15079 Recombinant Human NT-3 (E.coli) Recombinant human neurotrophic factor-3 was prepared by escherichia coli expression system and the target gene encoding Tyr139-Thr257 was expressed. Accession # : P20783.
M15078 Recombinant Mouse Noggin/NOG (HEK293,C-6His) Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466.
M15077 Recombinant Mouse LIF (E.coli) Mouse Leukemia inhibitory factor(lif)is a secreted protein which belongs to the LIF/OSM family. LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
M15076 Recombinant Mouse HGF (HEK293,C-6His) Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis.




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