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Recombinant Schistosoma Japonicum GST (E. coli)

Cat. No. M21326

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Schistosoma Japonicum GST (E. coli) Structure
Synonym:

Glutathione S-transferase class-mu 26 kDa isozyme; GST 26

Size Price Availability Quantity
10ug USD 100  USD100 In stock
50ug USD 160  USD160 In stock
500ug USD 540  USD540 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Glutathione S-Transferase (GST), an antioxidant enzyme, is involved in the primary cellular defense mechanism against reactive oxygen species. Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The activity of GSTs is dependent upon a steady supply of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove conjugates of GSH from the cell. The primary role of GSTs is to detoxify xenobiotics by catalyzing the nucleophilic attack by GSH on electrophilic carbon, sulfur, or nitrogen atoms of said nonpolar xenobiotic substrates, thereby preventing their interaction with crucial cellular proteins and nucleic acids.

Recombinant Schistosoma Japonicum GST expressed the target gene encoding Met1-Lys218.


Accession: P08515

Apparent Molecular Weight: 28 KDa, under reducing conditions

Endotoxin < 1 EU/µg

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] You Li, et al. Vet Parasitol. Establishment and evaluation of an iELISA using the recombinant membrane protein LHD-Sj23 for the serodiagnosis of Schistosoma japonicum infection in cattle in China

[2] Z Zhu, et al. Parasite Immunol. Protective efficacy evaluation induced by recombinant protein LHD-Sj23-GST of Schistosoma japonicum emulsified with three different adjuvants

[3] Man-jun Li, et al. Exp Parasitol. Cimetidine enhances the protective effect of GST DNA vaccine against Schistosoma japonicum

[4] Guangqing Yu, et al. J Huazhong Univ Sci Technolog Med Sci. Expression of recombinant baculovirus carrying Schistosoma japonicum 26 ku GST in mammalian cells

[5] Nobuo Ohta, et al. Parasitol Int. Research on calpain of Schistosoma japonicum as a vaccine candidate

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Keywords: Recombinant Schistosoma Japonicum GST (E. coli), Glutathione S-transferase class-mu 26 kDa isozyme; GST 26 supplier, Cytokines and Growth Factors, inhibitors, activators

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