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Recombinant Human NPPB (E.coli, N-6His)

Cat. No. M21347

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human NPPB (E.coli, N-6His) Structure
Synonym:

Natriuretic Peptides B; Gamma-Brain Natriuretic Peptide

Size Price Availability Quantity
10ug USD 200  USD200 In stock
50ug USD 505  USD505 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Genus: Human
Expression system: E.coli
Purity: >95% by reduced SDS-PAGE
Endotoxin: less than 0.1 ng/µg (1 EU/µg) by LAL test
Molecular weight: 14.2 KDa
Storage and stability: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C and stable for 3 months after opening under sterile conditions. Please minimize the freeze-thaw cycle.



Biological activity: Human natriuretic peptide B acts as a cardiac hormone; it is associated with many biological actions such as diuretic, diaphoretic, vasodilator and it inhibits the secretion of ranibulin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptide B can help restore the balance of salt and water in the body and improve cardiac function. Natriuretic peptide B binds to the NPR1 receptor and stimulates the production of cGMP, which binds to the clearance receptor NPR3.

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chenjie Liu, et al. Pak J Pharm Sci. Effect of metoprolol tartrate tablets and recombinant human B-type natriuretic peptide on the sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and heart failure

[2] Sanam Shafaattalab, et al. Front Cell Dev Biol. Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T ( TNNT2) Variant I79N

[3] Eline Huethorst, et al. J Physiol. Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytes

[4] Sbastien L'Hoste, et al. Biochim Biophys Acta. Characterization of the mouse ClC-K1/Barttin chloride channel

[5] M A Schumann, et al. J Biol Chem. Recombinant human tumor necrosis factor alpha induces calcium oscillation and calcium-activated chloride current in human neutrophils. The role of calcium/calmodulin-dependent protein kinase

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Keywords: Recombinant Human NPPB (E.coli, N-6His), Natriuretic Peptides B; Gamma-Brain Natriuretic Peptide supplier, Cytokines and Growth Factors, inhibitors, activators

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