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Recombinant Human CDH1 (HEK293, C-6His)

Cat. No. M21331

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human CDH1 (HEK293, C-6His) Structure
Synonym:

Cadherin-1; CDH1;CAM 120/80;E-cadherin; CD324

Size Price Availability Quantity
50ug USD 260  USD260 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

E-Cadherin is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. E-Cadherin has a potent invasive suppressor role and it is a ligand for integrin alpha-E/beta-7.

Recombinant Human Cadherin-1/E-Cadherin/CDH1 expressed the target gene encoding Asp155-Ile707 with a 6His tag at the C-terminus.


Accession: P12830

Apparent Molecular Weight: 80-90 KDa, reducing conditions

Endotoxin < 1 EU/µg

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Yoshiaki Usui, et al. N Engl J Med. Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

[2] Woojin Kim, et al. Gastrointest Endosc Clin N Am. Genetic Syndromes Associated with Gastric Cancer

[3] Han Lu, et al. Autophagy. Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence

[4] Ying-Hsia Chu, et al. Mod Pathol. Clinicopathologic features of kinase fusion-related thyroid carcinomas: an integrative analysis with molecular characterization

[5] Ziguo Zhang, et al. Biochem J. Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C)

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Keywords: Recombinant Human CDH1 (HEK293, C-6His), Cadherin-1; CDH1;CAM 120/80;E-cadherin; CD324 supplier, Cytokines and Growth Factors, inhibitors, activators

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