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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M25532 Recombinant Human PDGF-AA protein (E.coli) Recombinant Human PDGF-AA Protein is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M25530 Recombinant human Heregulin β-1 protein (CHO) Recombinant human Heregulin β-1 protein is a member of the EGF family of proteins. Heregulin is essential for the normal development of the nervous system and the heart. It is produced in numerous isoforms by alternative splicing, allowing it to perform a variety of functions.
M25484 Recombinant Human HBAZ Protein (E.coli, N-6His) Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. Recombinant Human Hemoglobin Subunit Zeta is produced by our E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus.
M25483 Recombinant Human HBQ1 Protein (E.coli, N-6His) Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Hemoglobin has a quaternary structure characteristically composed of many multi-subunit globular proteins. Recombinant Human Hemoglobin Subunit Theta-1 is produced by E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus.
M25480 Recombinant Human VWF Protein (CHO, His Tag) Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury.
M25476 Recombinant Streptococcus pyogenes CRISPR-Cas9 Protein (Baculovirus-Insect, His) The recombinant s. pyogenes serotype M1 cas9 consists of 1407 amino acids and predicts a molecular mass of 163 kDa.
M25441 Recombinant Human Endothelin B Receptor Protein (HEK293, His Tag) EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. The recombinant human EDNRB consists 86 amino acids and predicts a molecular mass of 9.5 kDa. A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with a polyhistidine tag at the C-terminus.
M25440 Recombinant Human Osteopontin/SPP1 Protein (HEK293, C-6His) Osteopontin/SPP1 is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Osteopontin/SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10.
M25427 Recombinant Human SDF-1 Protein (E. coli) The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription.
M25426 Recombinant Mouse SDF-1 Protein (E. coli) The stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription.
M25425 Recombinant Human CXCL10 (HEK293, C-Fc-6His) Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ.
M25424 Recombinant Human Fibronectin (Oryza sativa) Recombinant Human Fibronectin is an extracellular glycoprotein. As one of the major cell adhesion molecules, fibronectin plays a key role in many important physiological processes, such as embryogenesis, wound healing, hemostasis and thrombosis. Fibronectin can promote cell growth, increase cell apposition rate, enhance cell metabolism level and shorten cell growth time.
M25418 Recombinant Mouse IL-1β (CHO) Interleukin-1 Beta (IL-1β) (E. coli) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. ED50 < 10.0 pg/ml, measured in a cell proliferation assay using D10S cells, corresponding to a specific activity of > 1.0 × 108 units/mg.
M25412 Recombinant Human Midkine (E. coli) Midkine, also named MK, MK1, NEGF 2, is belonging to the neurotrophic and developmentally-regulated heparin-binding molecules family. Midkine promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis.
M25411 Recombinant Human CXCL1 (HEK293, C-6His) Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils.
M25406 Recombinant Human DLAT Protein (Baculovirus-Insect, His Tag) The recombinant human DLAT consists of 581 amino acids and predicts a molecular mass of 62.1 kDa. A DNA sequence encoding the human DLAT (NP_001922.2) (Ser87-Leu647) was expressed with a polyhistidine tag at the N-terminus.
M25405 Recombinant Protein G (E. coli) Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. Protein G was found to be a powerful reagent for the detection of IgG, and consequently the antigen against which these antibodies are directed. It was used in Western blot analyses to detect various antigen-antibody complexes on nitrocellulose membranes. Moreover, protein G is widely used as a ligand coupled to resins in affinity chromatography for antibody purification.
M25397 Recombinant Human Oncostatin M (OSM) (E. coli, 227aa) Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, including IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. ED50 < 10.0 ng/ml, measured by a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
M25396 Recombinant Human Oncostatin M (OSM) (E. coli, 209aa) Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. ED50 < 10.0 ng/ml, measured by a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
M25384 Recombinant Human KEAP1 Protein (Baculovirus-Insect, His & GST Tag) Kelch-like ECH-associated protein 1 (KEAP1) is a cytoplasm and nucleus protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain, and six Kelch repeats. KEAP1 is a key regulator of the NRF2 transcription factor, which transactivates the antioxidant response element (ARE) and upregulates numerous proteins involved in antioxidant defense.




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