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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M21723 Recombinant Human IL-17F (HEK293) Recombinant Human Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed. IL-17F can stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. The ED50 of Human IL-17F is 24.21 ng/ml.
M21721 Recombinant Mouse IGF-I Protein (E. coli) Recombinant Mouse IGF-I belongs to the IGF family of peptides, which also includes IGF-II and insulin. IGF-I executes its functions via signaling through transmembrane tyrosine receptors (IGF Receptors). ED50 < 10.0 ng/ml, measured by a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
M21719 Recombinant Human GDF-15/MIC-1 Protein (E. coli) The recombinant human GDF-15/MIC-1 is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.
M21714 Recombinant Human RANK (HEK293, C-6His) Recombinant Human RANK (C-6His) is produced by Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus.
M21713 Recombinant Mouse RANK (HEK293, C-6His) Recombinant Mouse RANK (Receptor Activator of NF-kappa B) is produced by Mammalian expression system and the target gene encoding Val31-Ser214 is expressed with a 6His tag at the C-terminus. RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation after binding its ligand RANKL.
M21707 Recombinant Mouse HSP70 Protein (HEK293, His Tag) HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles.
M21706 Recombinant Human IL-17F (HEK293, C-6His) Recombinant Human Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed with a 6His tag at the C-terminus. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor.
M21705 Recombinant Mouse IL-17F (HEK293, C-6His) Recombinant Mouse Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg29-Ala161 is expressed with a 6His tag at the C-terminus. Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
M21703 Recombinant Mouse Angiopoietin-1 Protein (HEK293, His Tag) Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system.
M21700 Recombinant Human Asprosin (HEK293, N-8His) Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream.
M21691 Recombinant Human IkB alpha Protein (E. coli, His Tag) IkB alpha (NFKBIA, IKBA) is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-kB's proper functioning.
M21686 Recombinant Mouse BAFF (HEK293, N-mFc) Recombinant Mouse BAFF (TNFSF13B/TNFSF20) belongs to the tumor necrosis factor family. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. The target gene encoding Ala127-Leu309 is expressed with a mFc tag at the N-terminus.
M21683 Recombinant Human IL-34 Protein (CHO, C-His) IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). Measured in a cell proliferation assay using human peripheral blood mononuclear cell, the ED50 is 2-8 ng/mL.
M21679 Recombinant Mouse IL-23 (HEK293) Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. Recombinant Mouse Interleukin-23 is produced by Mammalian expression system and the target gene encoding Val22-Ala196&Met23-Ser335 is expressed.
M21678 Recombinant Human IL-9 Protein (CHO) Recombinant Interleukin 9, also known as IL-9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. ED50 < 1.0 ng/ml, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1.0 × 106 units/mg.
M21677 Recombinant Human Follistatin 288 (HEK293, C-6His) Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid . Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein with a 29 aa signal sequence, and a 288 aa mature region. Recombinant Human Follistatin/FST is produced by Mammalian expression system and the target gene encoding Gly30-Asn317 is expressed with a 6His tag at the C-terminus.
M21671 Recombinant Mouse/Rat VEGF-C Protein (HEK293, aa 108-223, His Tag) Recombinant Mouse/Rat VEGF-C Protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC), the ED50 for this effect is typically 0.1-0.8 μg/mL.
M21670 Recombinant Mouse/Rat VEGF-C Protein (HEK293, aa 108-223, Fc Tag) Recombinant Mouse/Rat VEGF-C Protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC), the ED50 is typically 70-300 ng/mL.
M21666 Recombinant Mouse IL-18BPd (HEK293, C-Fc) Recombinant Mouse Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. Recombinant Mouse Interleukin-18 Binding Protein Isoform d is produced by our Mammalian expression system and the target gene encoding Thr29-Ala193 is expressed with a human IgG1 Fc tag at the C-terminus.
M21665 Recombinant Mouse IL-18 (E.coli, N-6His) Recombinant Mouse Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family, IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Recombinant Mouse Interleukin-18 is produced by E.coli expression system and the target gene encoding Asn36-Ser192 is expressed with a 6His tag at the N-terminus.




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