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Recombinant Human Fibronectin (Oryza sativa)

Cat. No. M25424
Recombinant Human Fibronectin (Oryza sativa) Structure
Synonym:

rhFN

Size Price Availability Quantity
1mg USD 200  USD200 In stock
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Quality Control & Documentation
  • Purity: ≥95%, Endotoxin < 0.5 EU/μg
  • COA
  • MSDS
Biological Activity

Recombinant Human Fibronectin is an extracellular glycoprotein. As one of the major cell adhesion molecules, fibronectin plays a key role in many important physiological processes, such as embryogenesis, wound healing, hemostasis and thrombosis. Fibronectin can promote cell growth, increase cell apposition rate, enhance cell metabolism level and shorten cell growth time. Fibronectin promotes the attachment and subsequent spreading of many cells. It is used for the coating of culture dishes.


Molecular Weight: 200~210 kDa

Endotoxin: < 0.5 EU/μg

Supplied as lyophilized powder, suitable for cell culture

Chemical Information
CAS Number 86088-83-7
Solubility (25°C) Reconstitute the lyophilized powder in PBS (pH 7.2~7.4) to prepare a 1 mg/mL stock solution. Divide the stock solution into individual dosages and stored at -20 ℃.
Storage Stored at -20°C for up to 2 years. The stock solution should be stable for up to 3 months at -20°C.
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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