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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (HEK293) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M40603 Recombinant Human IL-3 Protein (E. coli) Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
M40601 Recombinant Human IL-3 Protein (CHO) Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
M31387 Recombinant Human Growth Hormone (E. coli) Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors. It plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.
M31380 Recombinant Human HSP70 Protein (HEK293, N-His) HSP70 can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells.
M31361 Recombinant Human MRAP Protein (HEK293, hFc Tag) MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. A DNA sequence encoding the human MRAP (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus.
M31301 Recombinant Human VEGFR1 Protein (HEK293, C-Fc) Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 plays an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation, survival and angiogenesis in adulthood.
M31298 Recombinant Human CRHBP (HEK293, C-6His) Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
M31295 Recombinant Mouse IL-34 Protein (HEK293, C-His) IL-34 is a cytokine that promotes monocyte and macrophage differentiation and viability via colony-stimulating factor-1 receptor (CSF1R). The ED50 is 50-200 ng/mL as measured in a cell proliferation assay using M-NFS-60 mouse bone marrow cells.
M31178 Recombinant Human Beta-NGF Protein (E. coli) Human β-Nerve Growth Factor (β-NGF) is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.
M31176 Recombinant Human CD40L Protein (E. coli) CD40 Ligand (CD40L/CD154/TRAP) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. Recombinant Human CD40 Ligand is produced by E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
M31164 Recombinant Human PPARA Protein (E.coli, His Tag) The recombinant Human PPARA consists of 276 amino acids and predicts a molecular mass of 31.36 kDa. A DNA sequence encoding the Human PPARA (Q07869) (Thr200-Tyr468) was expressed, with a polyhistidine tag at the N-terminus.
M31163 Recombinant Mouse PPARA Protein (E.coli, His Tag) The recombinant Mouse PPARA consists of 276 amino acids and predicts a molecular mass of 31.49 kDa. A DNA sequence encoding the Mouse PPARA (P23204) (Thr200-Tyr468) was expressed, with a polyhistidine tag at the N-terminus.
M31146 Recombinant Human NRG2 Protein (HEK293, C-His) Neuregulin-2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. NRG2 plays a key role in nitrate regulation in part through modulating NRT1.1 expression and may function with NLP7 via their physical interaction.
M31139 Recombinant Human R-spondin-1/RSPO1 Protein (HEK293, C-6His) R-spondin-1/RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. Recombinant Human R-spondin-1 is produced by Mammalian expression system, and the target gene encoding Ser21-Ala263 is expressed with a 6His tag at the C-terminus.
M31138 Recombinant Mouse R-spondin-2/RSPO2 Protein (HEK293, mFc) R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling.
M31137 Recombinant Mouse R-spondin 1/RSPO1 Protein (CHO, C-His) R-Spondin-1 (Rspo-1) is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. In mice, RSPO1 induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
M31134 Recombinant Mouse Prolactin/PRL Protein (HEK293, C-6His) Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation.
M31133 Recombinant Mouse FGF-10/KGF-2 Protein (E. coli) Fibroblast Growth Factor-10 (FGF-10, also known as KGF-2) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions.
M31112 Recombinant Human IL-21 Protein (E. coli) IL-21 is expressed by CD4+ T cells, natural killer (NK) T cells, and Th17 cells. IL-21 plays a pivotal role in the survival and proliferation of B cells, and their differentiation to immunoglobulin (Ig) producing cells.
M31084 Recombinant Mouse IL-2 Protein (E. coli) Interleukin-2/IL-2 is a secreted protein that belongs to the IL-2 family. Interleukin-2/IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Interleukin-2 / IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.




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