All AbMole products are for research use only, cannot be used for human consumption.
Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT.
Measured in a cell proliferation assay using TF-1 cells, the ED50 is < 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 units/mg.
Apparent Molecular Weight: ~15.2 kDa
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml. |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
[2] A Kusumi et al. Gan To Kagaku Ryoho. [Interleukin 3 (IL-3)]
[3] S M MacDonald et al. J Immunol. Recombinant IL-3 induces histamine release from human basophils
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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