All AbMole products are for research use only, cannot be used for human consumption.
R-spondin-1/RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 augments the WNT/β catenin pathway to oppose male sex development. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. Recombinant Human R-spondin-1 is produced by Mammalian expression system, and the target gene encoding Ser21-Ala263 is expressed with a 6His tag at the C-terminus.
Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells, the ED50 for this effect is 4.06 ng/ml.
Accession: Q2MKA7
APMol Mass: 40 KDa, reducing conditions
Endotoxin < 0.01 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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