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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M40811 Recombinant Mouse CCL21 Protein (E. coli) C-C Motif Chemokine 21a (CCL21) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils.
M40805 Recombinant Human TPO (HEK293, N,C-6His) Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets.
M40779 Recombinant Influenza B Hemagglutinin/HA Protein (HEK293, C-His) Recombinant Influenza B Hemagglutinin / HA Protein is a homotrimer that recognizes target cells in vertebrates and does so by binding to salivary acid-containing receptors on these cells. When it binds to the target cell, it causes the host inner membrane to fuse with the viral membrane, thereby facilitating the entry of the viral genome into the target cell.
M40772 Recombinant Human CTLA-4 Protein (HEK293, C-Flag) Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal.
M40771 Recombinant Human CTLA-4 Protein (HEK293, C-6His) Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal.
M40746 Recombinant Human EGF Protein (E.coli) Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.
M40725 Recombinant Human PCNA Protein (Baculovirus-Insect, His) Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. PCNA also participates in the processing of branched intermediates that arise during the lagging strand DNA synthesis.
M40723 Recombinant Human KIAA0101 Protein (E. coli, His) KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). KIAA11 is involved in cell proliferation and plays a role in early tumor recurrence (ETR), and prognosis of hepatocellular carcinoma (HCC).
M40706 Recombinant Human PF-4/CXCL4 Protein (HEK293) Platelet factor 4 (PF-4/CXCL4) is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 can be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
M40683 Recombinant Human RBP4 (HEK293, C-His) Human-retinol binding protein is a single-chain polypeptide with a molecular weight of approximately 21000 and one binding site for retinol and other forms of vitamin A. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.
M40641 Recombinant Mouse MIF Protein (E.coli, C-6His) Macrophage migration inhibitory factor (MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.
M40612 Recombinant Rat IL-4 Protein (CHO, C-His) Interleukin-4 (IL-4) is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. IL-4 regulates the differentiation of native CD4+ T cells (Th0 cells) into helper Th2 cells, and regulates the immunoglobulin class switching to the IgG1 and IgE isotypes.
M40608 Recombinant Human IL18R1 (HEK293, C-6His) The interleukin 18 receptor 1 (IL18R1) belongs to interleukin 1 receptor family. IL18R1 has been shown to mediate EAE through regulation of both IL-18-dependent and -independent pathways.
M40606 Recombinant Human C5a Protein (E.coli) Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. Recombinant Human C5a expressed the target gene encoding Thr678-Arg751.
M40603 Recombinant Human IL-3 Protein (E. coli) Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
M40601 Recombinant Human IL-3 Protein (CHO) Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
M31387 Recombinant Human Growth Hormone (E. coli) Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors. It plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.
M31380 Recombinant Human HSP70 Protein (HEK293, N-His) HSP70 can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells.
M31361 Recombinant Human MRAP Protein (HEK293, hFc Tag) MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. A DNA sequence encoding the human MRAP (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus.
M31329 Recombinant Mouse IL-33 Protein (E. coli, 95%) Mouse Interleukin 33 (IL-33) may regulates gene transcription in producer cells. IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.




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