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Recombinant Mouse Fas Ligand Protein (Yeast, His Tag)

Cat. No. M45269

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse Fas Ligand Protein (Yeast, His Tag) Structure
Synonym:

FASLG; CD95L

Size Price Availability Quantity
50ug USD 450 In stock
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Quality Control & Documentation
  • Purity: >90%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Fas Ligand is the ligand for FAS, it is a transmembrane protein which binds to TNFRSF6/FAS. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

The recombinant mouse Fas Ligand consists of 158 amino acids and predicts a molecular mass of 18.2 kDa. A DNA sequence encoding the mouse Fas Ligand (Pro132-Leu279) was expressed with a polyhistidine tag at the N-terminus.


Endotoxin < 1 EU/µg

Lyophilized from sterile PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Dongjin Jeong, et al. Elife. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

[2] Yahui Song, et al. J Biol Chem. The mouse cell surface protein TOSO regulates Fas/Fas ligand-induced apoptosis through its binding to Fas-associated death domain

[3] Nobuaki Ozeki, et al. Arch Oral Biol. Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells

[4] Haidong Dong, et al. Nat Med. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

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Keywords: Recombinant Mouse Fas Ligand Protein (Yeast, His Tag), FASLG; CD95L supplier, Cytokines and Growth Factors, inhibitors, activators

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