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Recombinant Human IL-17B (HEK293, C-Fc)

Cat. No. M45121

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human IL-17B (HEK293, C-Fc) Structure
Synonym:

interleukin-17 beta

Size Price Availability
10ug USD 180  USD180 1-2 Weeks
50ug USD 440  USD440 1-2 Weeks
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.

Recombinant Human Interleukin-17B expressed the target gene encoding Gln21-Phe180 with a human IgG1 Fc tag at the C-terminus.


Accession: Q9UHF5

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 48 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Qingli Bie, et al. Oncogene. IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination

[2] Yuchao Chen, et al. Theranostics. Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8+ T-cell memory in wild-type and humanized mice

[3] Jessica E Miller, et al. Front Immunol. IL-17A Modulates Peritoneal Macrophage Recruitment and M2 Polarization in Endometriosis

[4] Jacob S Lee, et al. Immunity. Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

[5] Gao-qin Liu, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. [Eukaryotic expression and biological activity of recombinant human IL-17B protein]

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Keywords: Recombinant Human IL-17B (HEK293, C-Fc), interleukin-17 beta supplier, Cytokines and Growth Factors, inhibitors, activators

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