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β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type domain, which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. B2M might be involved in the OA (osteoarthritis) pathogenesis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders.
Recombinant Human B2M/Beta-2-Microglobulin expressed the target gene encoding Ile21-Met119 with a 6His tag at the N-terminus.
Accession: P61769
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 14 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[4] Maximilian Brinkhaus, et al. Sci Rep. Human IgE does not bind to human FcRn
[5] Aurélie Auguste, et al. Bull Cancer. [Abnormalities of DNA repair and gynecological cancers]
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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