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Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 is involved in muscular dystrophies.
Recombinant Human Annexin A2 expressed the target gene encoding Ser2-Asp339.
Accession: P07355
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 35 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 6% Sucrose, 4% Mannitol, 0.05%Tween 80, pH 5.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[4] R Weiss, et al. J Autoimmun. Annexin A2, autoimmunity, anxiety and depression
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