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Recombinant Human uPA (HEK293, C-6His)

Cat. No. M45059

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human uPA (HEK293, C-6His) Structure
Synonym:

Urokinase-Type Plasminogen Activator; U-Plasminogen Activator

Size Price Availability Quantity
10ug USD 275  USD275 In stock
50ug USD 720  USD720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Recombinant Human Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Urokinase-Type Plasminogen Activator specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

Recombinant Human Urokinase-Type Plasminogen Activator/uPA expressed the target gene encoding Ser21-Leu431 with a 6His tag at the C-terminus.


Accession: P00749

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 45-55 KDa, reducing conditions

Supplied as a 0.2 μm filtered solution of 20mM HEPES, 2mM CaCl2, 10% Glycerol, pH 7.4.

This product is shipped on dry ice. Upon receipt, store it immediately at the temperature listed below.

Chemical Information
Form Solution
Storage Store at ≤ -70°C, stable for 6 months after receipt.
References

[1] Tao Song, et al. Int J Clin Exp Pathol. The overexpression of uPA promotes the proliferation and fibrinolytic activity of human umbilical vein endothelial cells

[2] Rais Reskiawan A Kadir, et al. Cell Mol Neurobiol. Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke

[3] Manman Su, et al. Int J Oncol. Expression and anticancer activity analysis of recombinant human uPA1‑43-melittin

[4] Weimin Zhou. Mol Med Rep. Effect of adenovirus‑mediated uPA gene transduction on the fibrinolytic activity of human umbilical vein endothelial cells

[5] O Wilhelm, et al. FEBS Lett. Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells

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Keywords: Recombinant Human uPA (HEK293, C-6His), Urokinase-Type Plasminogen Activator; U-Plasminogen Activator supplier, Cytokines and Growth Factors, inhibitors, activators

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