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Recombinant Human B7-H3/CD276 Protein (HEK293, C-6His)

Cat. No. M45176

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human B7-H3/CD276 Protein (HEK293, C-6His) Structure
Synonym:

B7 homolog 3; CD276 antigen

Size Price Availability Quantity
10ug USD 215  USD215 In stock
50ug USD 620  USD620 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

B7-H3 (also known as CD276) is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is involved in the activation of T lymphocytes, and regulates murine bone formation. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes.

Recombinant Human B7-H3 expressed the target gene encoding Leu29-Thr461 with a 6His tag at the C-terminus.

Immobilized Human B7-H3-His at 2μg/ml (100 μl/well) can bind Anti-Human B7-H3 mAb.


Accession: Q5ZPR3

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 65-90 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Sunao Sugita, et al. Int J Mol Sci. Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals

[2] Ruonan Feng, et al. Antib Ther. Isolation of rabbit single domain antibodies to B7-H3 via protein immunization and phage display

[3] Murali Janakiram, et al. Immunol Rev. The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3

[4] Jian Shi, et al. Mol Med Rep. Preparation and application of a novel monoclonal antibody specific for human B7-H3

[5] Y Luan, et al. J Viral Hepat. Potential role of soluble B7-H3 in liver immunopathogenesis during chronic HBV infection

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Keywords: Recombinant Human B7-H3/CD276 Protein (HEK293, C-6His), B7 homolog 3; CD276 antigen supplier, Cytokines and Growth Factors, inhibitors, activators

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