All AbMole products are for research use only, cannot be used for human consumption.
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription. SDF-1/CXCL12 has crucial roles in the formation of multiple organ systems during embryogenesis and in the regulation of bone marrow haematopoiesis and immune function in the postnatal organism.
Recombinant Human SDF-1 is produced by E.coli expression system and the target gene encoding Lys 22-Met 93 is expressed.
The recombinant human SDF-1 consists of 73 amino acids and predicts a molecular mass of 8.6 kDa. It migrates as an approximately 12 kDa band in SDS-PAGE under reducing conditions.
Accession: P48061
Endotoxin: < 1.0 EU per μg protein as determined by LAL test
Lyophilized from sterile PBS, pH 7.4.
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
| Storage | Stable for up to twelve months from date of receipt at -20℃ to -80℃ |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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