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Recombinant Human PTH1R (HEK293, C-6His)

Cat. No. M40874

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human PTH1R (HEK293, C-6His) Structure
Synonym:

Parathyroid Hormone 1 Receptor

Size Price Availability Quantity
10ug USD 180  USD180 In stock
50ug USD 415  USD415 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

Parathyroid hormone 1 receptor (PTH1R) is a protein that in humans is encoded by the PTH1R gene, it belongs to the G-protein coupled receptor 2 family. PTH1R functions as a receptor for parathyroid hormone (PTH) and for parathyroid hormone-related protein (PTHrP). Recombinant Human Parathyroid Hormone 1 Receptor expressed the target gene encoding Tyr23-Met189 with a 6His tag at the C-terminus.


Accession: Q03431

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 25-35 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Eileen J Daley et al. Endocrinology. Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice

[2] Junko Shimomura-Kuroki et al. Odontology. Characterization of a PTH1R missense mutation responsible for Jansen type metaphyseal chondrodysplasia

[3] Brittany N Bohinc et al. Prog Mol Biol Transl Sci. Arrestins in bone

[4] Bin Wang et al. J Biomol Tech. Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase

[5] David W Dempster et al. J Cell Biochem. Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblasts

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Keywords: Recombinant Human PTH1R (HEK293, C-6His), Parathyroid Hormone 1 Receptor supplier, Cytokines and Growth Factors, inhibitors, activators

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