Human serum albumin is a protein found in human plasma. Its non-glycosylated, single-chain polypeptide contains 585 amino acids, has a molecular weight of 66 kD, transports fatty acids, bile pigments, amino acids, and steroid hormones, and serves as an excipient, stabilizer, and encapsulant.
| CAS Number | 70024-90-7 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[5] Stephane Arques. Eur J Intern Med. Human serum albumin in cardiovascular diseases
| Related Solvents & Excipients Products |
|---|
| Dimethyl sulfoxide
Dimethyl sulfoxide (DMSO) is a commonly used organic solvent with high solvency capacity, soluble in most organic substances such as water, ethanol, propanol, ether, benzene and chloroform, and can be used for the dissolution of compounds and other products. |
| ATX-002
ATX-002 is an ionizable cationic lipid for RNA drug delivery with theoretical pKa (c-pKa) and measured pKa values of 8.68 and 6.03, respectively. |
| 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE is a phospholipid that can be used in studies related to drug delivery. |
| PEG1500
PEG1500 is a polymer produced by the condensation reaction of ethylene oxide and water, generally white waxy solid in appearance, often used as a pharmaceutical excipient. |
| PLGA lactide:glycolide (50:50) (MW 90000)
PLGA lactide:glycolide (50:50) (MW 90000) Poly(D,L-propylidene-CO-ethylidene glycolide) is a synthetic amino acid that can be used for macromolecular delivery. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
