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Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. The recombinant human TSHR consists of 404 amino acids and predicts a molecular mass of 46.1 kDa. A DNA sequence encoding the human TSHR (Gly21-Gly413) was expressed with a polyhistidine tag at the C-terminus.
Endotoxin < 1 EU/µg
Lyophilized from sterile 50mM Tris, 150mM NaCl, 10% Glycerol, 1mM TCEP, pH 7.5.
| Form | Lyophilized powder |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[2] Christopher W Rowe et al. Endocr Relat Cancer. Targeting the TSH receptor in thyroid cancer
[3] R A Ajjan et al. Nat Clin Pract Endocrinol Metab. Techniques to quantify TSH receptor antibodies
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