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Platelet factor 4 (PF-4/CXCL4) is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 can be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Measured by the ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells, the ED50 is < 10.0 ug/ml.
Accession: P02776
Apparent Molecular Weight: ~7.8 kDa
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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