Cat.No. | Name | Information |
---|---|---|
M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
M3471 | Ketorolac | Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
M3362 | Tolfenamic Acid | Tolfenamic Acid is a COX-2 inhibitor, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1. |
M3360 | Zaltoprofen | Zaltoprofen is an orally active COX inhibitor with IC50 values of 1.3 and 0.34 μM for COX-1 and COX-2, respectively, and possesses potent anti-inflammatory activity. |
M3308 | Asaraldehyde | Asaraldehyde is a natural COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1. |
M3203 | Lornoxicam | Lornoxicam is a COX-1 and COX-2 inhibitor with IC50 of 5 nM and 8 nM, respectively. |
M3148 | ATB 346 | ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity. |
M3112 | Valdecoxib | Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM. |
M3089 | Triflusal | Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1. |
M3079 | Tolmetin Sodium | Tolmetin Sodium is an aromatic alkyic acid non - steroidal anti - inflammatory compound. |
M3024 | Sodium salicylate | Sodium salicylate is used in medicine as an analgesic and antipyretic. |
M2984 | Rofecoxib | Rofecoxib is a COX-2 inhibitor with IC50 of 18 nM. |
M2905 | Oxaprozin | Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory compound (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. |
M2871 | Nabumetone | Nabumetone is a non-steroidal anti-inflammatory compound and its active metabolite inhibits the COX. |
M2835 | Mefenamic Acid | Mefenamic Acid is a competitive inhibitor of COX-1 and COX-2. |
M2817 | Meclofenamate sodium | Meclofenamate sodium is a dual COX-1/COX-2 inhibitor with an IC50 of 40 nM and 50 nM, respectively. used in the study of joint and muscle pain, arthritis, and dysmenorrhea. meclofenamate sodium is a non-selective gap-junction blocker and a highly selective inhibitor of adipose and obesity-associated enzyme (FTO) inhibitor. |
M2706 | Flufenamic acid | Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator. |
M2634 | Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
M2633 | Diclofenac Diethylamine | Diclofenac diethylamine is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
M2478 | Bufexamac | Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM. |
M2471 | Bromfenac Sodium | Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. |
M2392 | Ampiroxicam | Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
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