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Isofraxidin is an anti-bacterial, anti-oxidant, and anti-inflammatory agent, it acts by reducing the levels of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and prostaglandin E2 (PGE2), inhibiting cyclooxygenase-2 (COX-2) protein expression. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells.
| Molecular Weight | 222.19 |
| Formula | C11H10O5 |
| CAS Number | 486-21-5 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related COX Products |
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| PPOH
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. |
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| COX-2-IN-6
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