| Cat.No. | Name | Information |
|---|---|---|
| M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
| M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
| M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
| M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
| M3466 | Indomethacin | Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin can be used for cancer, inflammation and viral infection research. |
| M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
| M3471 | Ketorolac tromethamine salt | Ketorolac tromethamine salt (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
| M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
| M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
| M3915 | Catechin | Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. |
| M19361 | Rosmanol | Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. |
| M19356 | Columbin | Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM). |
| M17903 | Gamma-Mangostin | Gamma-Mangostin (γ-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities. |
| M14083 | Paradol | Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site. |
| M14080 | Gallic acid hydrate | Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). |
| M11002 | N-tert-Butyl-α-phenylnitrone | N-tert-Butyl-α-phenylnitrone is a nitrokeone-based free radical scavenger that forms a nitric oxide spin adduct. N-tert-Butyl-α-phenylnitrone inhibits the catalytic activity of COX2. |
| M10989 | (+)-Catechin hydrate | (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1), with IC50 of 1.4 μM. |
| M10920 | Chebulagic acid | Chebulagic acid is a dual inhibitor of COX-LOX extracted from the fruit. Has anti-inflammatory and anti-infective effects. Chebulagic acid is an M2(S31N) inhibitor and anti-influenza virus agent. Chebulagic acid also inhibits replication of the SARS-CoV-2 virus,EC50 The value is 9.76 μM. |
| M10580 | Guaiacol | Guaiacol is a phenolic compound, which inhibits LPS-stimulated COX-2 expression and NF-κB activation, with anti-inflammatory activity. |
| M10099 | CAY10404 | CAY10404 is one of the most selective inhibitors of COX-2 (IC50 = 1 nM) over COX-1. |
| M9682 | TFAP | TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM. |
| M8277 | 680C91 | 680C91 is a potent inhibitor of the enzyme tryptophan 2,3-dioxygenase (TDO), which directs the conversion of trypophan to kynurenin. |
| M8040 | SC-236 | Sc-236 is a COX-2 specific inhibitor with an IC50 value of 10 nM for COX-1 and a PPARγ agonist with oral activity. Sc-236 inhibits activator protein-1 (AP-1) activity by c-Jun amino terminus. Sc-236 exerts anti-inflammatory effects by inhibiting ERK phosphorylation in mouse models. |
| M7274 | SC 560 | SC 560 is a cyclooxygenase-1 (COX-1) inhibitor. |
| M7051 | NS-398 | NS-398 is a cyclooxygenase-2 (COX-2) inhibitor, selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects. |
| M6693 | DuP 697 | DuP 697 is a cyclooxygenase-2 (COX-2) inhibitor. |
| M6057 | α-Vitamin E (D-α-Tocopherol) | Vitamin E (D-alpha-Tocopherol) is a naturally occurring form of Vitamin E that is a potent antioxidant. |
| M5996 | Tenoxicam | Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM. |
| M5985 | Suprofen | Suprofen is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic. |
| M5945 | Salicylic acid | Salicylic acid is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
