COX Cyclooxygenase

Cat.No.	Name	Information
M3264	Pravadoline	Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist.
M2495	Carprofen	Carprofen inhibits canine COX2 with IC50 of 0.03 mM.
M3359	Ibuprofen	Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.
M3936	Saikosaponin D	Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis.
M1965	Celecoxib	Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively).
M3471	Ketorolac	Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.
M20423	Etoricoxib	Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.
M2824	Lumiracoxib	Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and K_i of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1.
M10099	CAY10404	CAY10404 is one of the most selective inhibitors of COX-2 (IC50 = 1 nM) over COX-1.
M9682	TFAP	TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM.
M8277	680C91	680C91 is a potent inhibitor of the enzyme tryptophan 2,3-dioxygenase (TDO), which directs the conversion of trypophan to kynurenin.
M8040	SC-236	Sc-236 is a COX-2 specific inhibitor with an IC50 value of 10 nM for COX-1 and a PPARγ agonist with oral activity. Sc-236 inhibits activator protein-1 (AP-1) activity by c-Jun amino terminus. Sc-236 exerts anti-inflammatory effects by inhibiting ERK phosphorylation in mouse models.
M7274	SC 560	SC 560 is a cyclooxygenase-1 (COX-1) inhibitor.
M7051	NS 398	NS 398 is a cyclooxygenase-2 (COX-2) inhibitor.
M6693	DuP 697	DuP 697 is a cyclooxygenase-2 (COX-2) inhibitor.
M6057	Vitamin E (D-alpha-Tocopherol)	Vitamin E (D-alpha-Tocopherol) is a naturally occurring form of Vitamin E that is a potent antioxidant.
M5996	Tenoxicam	Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM.
M5985	Suprofen	Suprofen is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic.
M5945	Salicylic acid	Salicylic acid is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.
M5923	Rebamipide	Rebamipide (OPC12759) is a cholecystokinin-1 (CCK1) receptor inhibitor that inhibits [125I]BH-CCK-8S with an IC50 of 37.7 μM. Rebamipide is an orally effective gastroprotective agent. Rebamipide enhances the production of endogenous PGs (particularly intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide also has anti-proliferative activity against gastric cancer cells.
M5907	Propyphenazone	Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
M5893	Pranoprofen	Pranoprofen is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.
M5874	Phenacetin	Phenacetin is a non-opioid analgesic without anti-inflammatory properties.
M5859	Parecoxib Sodium	Parecoxib is a potent and selective COX-2 inhibitor.
M5858	Parecoxib	Parecoxib is a selective COX2 inhibitor.
M5814	Niflumic acid	Niflumic acid is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.
M5755	Loxoprofen	Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.
M5716	Isoxicam	Isoxicam is a new non-steroidal anti-inflammatory benzothiazine derivative.

By Signaling Pathways

By Product Type

Signaling Pathways

COX Cyclooxygenase

Get to Know Us

Customer Support

Resources

Contact Us