Cat.No. | Name | Information |
---|---|---|
M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
M3466 | Indomethacin | Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin can be used for cancer, inflammation and viral infection research. |
M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
M3471 | Ketorolac tromethamine salt | Ketorolac tromethamine salt (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
M3915 | Catechin | Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. |
M2905 | Oxaprozin | Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory compound (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. |
M2871 | Nabumetone | Nabumetone is a non-steroidal anti-inflammatory compound and its active metabolite inhibits the COX. |
M2817 | Meclofenamate sodium | Meclofenamate sodium is a dual COX-1/COX-2 inhibitor with an IC50 of 40 nM and 50 nM, respectively. used in the study of joint and muscle pain, arthritis, and dysmenorrhea. meclofenamate sodium is a non-selective gap-junction blocker and a highly selective inhibitor of adipose and obesity-associated enzyme (FTO) inhibitor. |
M2706 | Flufenamic acid | Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator. |
M2634 | Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
M2633 | Diclofenac Diethylamine | Diclofenac diethylamine is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
M2478 | Bufexamac | Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM. |
M2471 | Bromfenac Sodium | Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. |
M2392 | Ampiroxicam | Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
M2233 | Nepafenac | Nepafenac is an analgesic selective inhibitor of COX-2. |
M1830 | Firocoxib | Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2. |
M56352 | PPOH | PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. |
M56351 | Tenidap | Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. |
M56350 | COX-2-IN-6 | COX-2-IN-6 is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. |
M56349 | Tazofelone | Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. |
M56348 | (S)-Ketorolac | (S)-Ketorolac is a nonsteroidal anti-inflammatory agent. |
M56347 | Benoxaprofen | Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. |
M56346 | Ibuprofen sodium | Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. |
M56345 | Eicosatetraynoic acid | Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). |
M54842 | Oxyphenbutazone | Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis. |
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