| Cat.No. | Name | Information |
|---|---|---|
| M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
| M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
| M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
| M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
| M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
| M3471 | Ketorolac | Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
| M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
| M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
| M18275 | N-trans-Feruloyltyramine | N-trans-Feruloyltyramine |
| M18271 | Ethyl p-methoxycinnamate | Ethyl p-methoxycinnamate |
| M18165 | Clematomandshurica saponin B | Clematomandshurica saponin B |
| M18159 | 2,4,5-Trimethoxybenzaldehyde | 2,4,5-Trimethoxybenzaldehyde |
| M17992 | 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone | 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone |
| M14084 | Salicin | Salicin is a natural COX inhibitor. |
| M14082 | Naproxen | Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. |
| M14081 | Indomethacin sodium hydrate | Indomethacin sodium hydrate (Indometacin sodium hydrate) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. |
| M11449 | AG-024322 | Ag-024322 is a potent ATP-competitive pan-CDK inhibitor that inhibits THE Ki values of CDK1, CDK2, and CDK4 in the 1-3 nM range. Ag-024322 showed broad spectrum antitumor activity and clear target regulation in vivo. Ag-024322 induced apoptosis. |
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