Cat.No. | Name | Information |
---|---|---|
M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
M3466 | Indomethacin | Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin can be used for cancer, inflammation and viral infection research. |
M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
M3471 | Ketorolac tromethamine salt | Ketorolac tromethamine salt (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
M3915 | Catechin | Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. |
M5923 | Rebamipide | Rebamipide (OPC12759) is a cholecystokinin-1 (CCK1) receptor inhibitor that inhibits [125I]BH-CCK-8S with an IC50 of 37.7 μM. Rebamipide is an orally effective gastroprotective agent. Rebamipide enhances the production of endogenous PGs (particularly intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide also has anti-proliferative activity against gastric cancer cells. |
M5907 | Propyphenazone | Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors. |
M5893 | Pranoprofen | Pranoprofen is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology. |
M5874 | Phenacetin | Phenacetin is a non-opioid analgesic without anti-inflammatory properties. |
M5859 | Parecoxib Sodium | Parecoxib Sodium (SC 69124A) is a potent and highly selective and orally active COX-2 inhibitor. Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. |
M5858 | Parecoxib | Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. |
M5814 | Niflumic acid | Niflumic acid is an inhibitor of cyclooxygenase-2 used for joint and muscular pain. |
M5755 | Loxoprofen | Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group. |
M5716 | Isoxicam | Isoxicam is a new non-steroidal anti-inflammatory benzothiazine derivative. |
M5703 | Iguratimod | Iguratimod(T-614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. |
M5677 | Psoralidin | Psoralidin, a natural furanocoumarin, is isolated from Psoralea corylifolia L. possessing anti-cancer properties. |
M5658 | Flurbiprofen | Flurbiprofen is a phenylalkanic acid derivative, which is a non-steroidal anti-inflammatory compound (NSAIDs). |
M5655 | Flunixin Meglumin | Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. |
M5643 | Fenoprofen Calcium hydrate | Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID). |
M5639 | Fenbufen | Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug. |
M5634 | Etodolac | Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain. |
M5574 | Diflunisal | Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor. |
M5572 | Diclofenac | Diclofenac (diclofenac) is a COX inhibitor and has an IC50 of 60 and 220 nM for sheep COX-1 and -2, respectively. |
M5381 | Acemetacin | Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor. |
M5379 | Aceclofenac | Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. |
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