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COX Cyclooxygenase

Cat.No.  Name Information
M3264 Pravadoline Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist.
M2495 Carprofen Carprofen inhibits canine COX2 with IC50 of 0.03 mM.
M3359 Ibuprofen Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.
M3936 Saikosaponin D Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis.
M3466 Indomethacin Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin can be used for cancer, inflammation and viral infection research.
M1965 Celecoxib Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively).
M3471 Ketorolac tromethamine salt Ketorolac tromethamine salt (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.
M20423 Etoricoxib Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.
M2824 Lumiracoxib Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1.
M3915 Catechin Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
M5923 Rebamipide Rebamipide (OPC12759) is a cholecystokinin-1 (CCK1) receptor inhibitor that inhibits [125I]BH-CCK-8S with an IC50 of 37.7 μM. Rebamipide is an orally effective gastroprotective agent. Rebamipide enhances the production of endogenous PGs (particularly intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide also has anti-proliferative activity against gastric cancer cells.
M5907 Propyphenazone Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
M5893 Pranoprofen Pranoprofen is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.
M5874 Phenacetin Phenacetin is a non-opioid analgesic without anti-inflammatory properties.
M5859 Parecoxib Sodium Parecoxib Sodium (SC 69124A) is a potent and highly selective and orally active COX-2 inhibitor. Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis.
M5858 Parecoxib Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis.
M5814 Niflumic acid Niflumic acid is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.
M5755 Loxoprofen Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.
M5716 Isoxicam Isoxicam is a new non-steroidal anti-inflammatory benzothiazine derivative.
M5703 Iguratimod Iguratimod(T-614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor.
M5677 Psoralidin Psoralidin, a natural furanocoumarin, is isolated from Psoralea corylifolia L. possessing anti-cancer properties.
M5658 Flurbiprofen Flurbiprofen is a phenylalkanic acid derivative, which is a non-steroidal anti-inflammatory compound (NSAIDs).
M5655 Flunixin Meglumin Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity.
M5643 Fenoprofen Calcium hydrate Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
M5639 Fenbufen Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
M5634 Etodolac Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.
M5574 Diflunisal Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.
M5572 Diclofenac Diclofenac (diclofenac) is a COX inhibitor and has an IC50 of 60 and 220 nM for sheep COX-1 and -2, respectively.
M5381 Acemetacin Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
M5379 Aceclofenac Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.




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