Cat.No. | Name | Information |
---|---|---|
M3264 | Pravadoline | Pravadoline (WIN 48098) is a cyclooxygesase inhibitor and inhibits prostaglandin synthesis with IC50 of 4.9 μM, also a cannabinoid agonist. |
M2495 | Carprofen | Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
M3359 | Ibuprofen | Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
M3936 | Saikosaponin D | Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. |
M1965 | Celecoxib | Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
M3471 | Ketorolac | Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
M20423 | Etoricoxib | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
M2824 | Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. |
M5703 | Iguratimod | Iguratimod(T-614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. |
M5677 | Psoralidin | Psoralidin, a natural furanocoumarin, is isolated from Psoralea corylifolia L. possessing anti-cancer properties. |
M5658 | Flurbiprofen | Flurbiprofen is a phenylalkanic acid derivative, which is a non-steroidal anti-inflammatory compound (NSAIDs). |
M5655 | Flunixin Meglumin | Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. |
M5643 | Fenoprofen Calcium hydrate | Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID). |
M5639 | Fenbufen | Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug. |
M5634 | Etodolac | Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain. |
M5574 | Diflunisal | Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor. |
M5572 | Diclofenac | Diclofenac (diclofenac) is a COX inhibitor and has an IC50 of 60 and 220 nM for sheep COX-1 and -2, respectively. |
M5381 | Acemetacin | Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor. |
M5379 | Aceclofenac | Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. |
M5366 | 4-Aminoantipyrine | 4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. |
M5361 | 2-Ethoxybenzamide | 2-ethoxybenzamide is a common analgesic and anti-inflammatory compound used to relieve fever, fever, headache and other mild pain. |
M5352 | (R)-(-)-Ibuprofen | (R)-Ibuprofen, a nonsteroidal anti-inflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2. |
M5351 | (+/-)-Sulfinpyrazone | Sulfinpyrazone is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules. |
M5185 | Xanthohumol | Xanthohumol is an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV). |
M4761 | Avicularin | Avicularin is a bioactive flavonoid found in a variety of plants. It has anti-inflammatory, anti-allergy, anti-oxidation, liver protection, anti-tumor and other effects. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. In LPS-stimulated RAW 264.7 macrophages, Avicularin produces anti-inflammatory activity by inhibiting the ERK signaling pathway. |
M4673 | Esculentoside-A | Esculentoside A (EsA), A triterpenoid saponin isolated from the root of Phytolacca esculenta. |
M4667 | Homoorientin | Homoorientin (Isoorientin) is a potent inhibitor of COX-2 with an IC50 value of 39 μM. |
M4655 | Byakangelicol | Byakangelicol is white triol separated from Angelica dahurica, Interleukin-1 β (IL-1β) -induced release of prostaglandin E2 (PGE2) in A549 cells was inhibited by inhibiting the expression and activity of coX-2. Byakangelicol can be used to study airway inflammation. |
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