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Naproxen (Aleve) is a non-selective cyclooxygenase (COX) inhibitor with IC50 of 8.7 ?0.23 mg/kg. It displays anti-inflammatory, antipyretic and analgesic effects and has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Molecular Weight | 252.24 |
Formula | C14H13NaO3 |
CAS Number | 26159-34-2 |
Solubility (25°C) | Water 70 mg/mL Ethanol 10 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yahiya Y Syed. Sumatriptan/Naproxen Sodium: A Review in Migraine
[3] Lily P H Yang. Sumatriptan/naproxen sodium: a review of its use in adult patients with migraine
[4] Catalina Cleves, et al. Sumatriptan/naproxen sodium combination for the treatment of migraine
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Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine significantly inhibits high COX-2 activity. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. |
PPOH
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. |
Tenidap
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COX-2-IN-6
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