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Naproxen (Aleve) is a non-selective cyclooxygenase (COX) inhibitor with IC50 of 8.7 ?0.23 mg/kg. It displays anti-inflammatory, antipyretic and analgesic effects and has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
| Molecular Weight | 252.24 |
| Formula | C14H13NaO3 |
| CAS Number | 26159-34-2 |
| Solubility (25°C) | Water 70 mg/mL Ethanol 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yahiya Y Syed. Sumatriptan/Naproxen Sodium: A Review in Migraine
[3] Catalina Cleves, et al. Sumatriptan/naproxen sodium combination for the treatment of migraine
| Related COX Products |
|---|
| Firocoxib
Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2. |
| Ampiroxicam
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
| Bufexamac
Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM. |
| Carprofen
Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
| Diclofenac Diethylamine
Diclofenac diethylamine is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
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