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Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
| Molecular Weight | 308.31 |
| Formula | C13H12N2O5S |
| CAS Number | 51803-78-2 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Jeongyoon Kwon, et al. Nimesulide-induced hepatotoxicity: A systematic review and meta-analysis
[3] C Mattia, et al. Nimesulide: 25 years later
| Related COX Products |
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Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory agent from the enol-carboxamide class. |
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| PPOH
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. |
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| COX-2-IN-6
COX-2-IN-6 is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. |
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