About 2 results found for searched term "PDHK" (0.14 seconds)
Cat.No. | Name | Target |
---|---|---|
M2423 | AZD7545 | PDK1 |
AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. | ||
M30913 | TM-1 | PDHK |
TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation. |
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