All AbMole products are for research use only, cannot be used for human consumption.
Puromycin dihydrochloride is a protein synthesis inhibitor. Puromycin 2HCl leads to the premature release of polypeptide chains as polypeptidyl purine derivatives. Analog of the 3' end of aminoacyl-tRNA. Puromycin dihydrochloride Inhibits translation in both in vitro and in vivo systems. Puromycin dihydrochloride inhibits the transport of proteins into the mitochondria in vitro. Puromycin inhibits protein import into mitochondria by interfering with an ATP-dependent step in the import process and that the ATP-dependent component in the reaction is located inside the inner mitochondrial membrane.
Biochim Biophys Acta Mol Basis Dis. 2024 Jul 15;1870(7):167355..
A novel HOIP frameshift variant alleviates NF-kappaB signalling and sensitizes cells to TNF-induced death
Puromycin dihydrochloride purchased from AbMole
Biochim Biophys Acta Mol Basis Dis. 2024 Oct 25.
TMEM106B knockdown exhibits a neuroprotective effect in Parkinson's disease models via regulating autophagy-lysosome pathway
Puromycin dihydrochloride purchased from AbMole
J Ethnopharmacol. 2023 Feb 10;302(Pt A):115897.
Total glucosides of paeony alleviates scleroderma by inhibiting type I interferon responses
Puromycin dihydrochloride purchased from AbMole
Transl Oncol. 2023 Feb;28;101617.
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation
Puromycin dihydrochloride purchased from AbMole
Nucleic Acids Res. 2021 Mar 18;49(5):2848-2858.
HuB and HuD repress telomerase activity by dissociating HuR from TERC
Puromycin dihydrochloride purchased from AbMole
Int J Chron Obstruct Pulmon Dis. 2021 Jun 4;16:1661-1675.
Histone Deacetylase 2 Suppresses Skeletal Muscle Atrophy and Senescence via NF-κB Signaling Pathway in Cigarette Smoke-Induced Mice with Emphysema
Puromycin dihydrochloride purchased from AbMole
DNA Cell Biol. 2021 Jul;40(7):895-905.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5
Puromycin dihydrochloride purchased from AbMole
Nature. 2020 Dec;588(7839):664-669.
Creation of bladder assembloids mimicking tissue regeneration and cancer
Puromycin dihydrochloride purchased from AbMole
Cell Death Dis. 2020 Oct 23;11(10):902.
The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma
Puromycin dihydrochloride purchased from AbMole
Environ Health Perspect. 2020 Jun;128(6):67008.
Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation
Puromycin dihydrochloride purchased from AbMole
Exp Biol Med (Maywood). 2020 Jun;245(11):925-932.
Circular RNA circ-CDYL sponges miR-1180 to elevate yes-associated protein in multiple myeloma
Puromycin dihydrochloride purchased from AbMole
| Molecular Weight | 544.43 |
| Formula | C22H29N7O5.2HCl |
| CAS Number | 58-58-2 |
| Solubility (25°C) | Water ≥ 30 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Animal Modeling Products |
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| Sodium Thioglycolate
Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth. Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo. |
| Vancomycin-d10 2TFA salt
Vancomycin-d10 2TFA salt |
| Acetic acid-d4
Acetic acid-d4 |
| Myosin H Chain Fragment, mouse acetate
Myosin H Chain Fragment, mouse acetate salt is a fragment of the α-Myosin heavy chain peptide. Myosin H Chain Fragment can be used to induce experimental autoimmune myocarditis (EAM) mouse model. |
| Myosin H Chain Fragment, mouse
Myosin H Chain Fragment, mouse is a fragment of the α-Myosin heavy chain peptide. Myosin H Chain Fragment can be used to induce experimental autoimmune myocarditis (EAM) mouse model. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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