DAPI dihydrochloride is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.
Appl Biochem Biotechnol Appl Biochem Biotechnol. 2022 Jul 1.
Apatinib Through Activating the RhoA/ROCK Signaling Pathway to Cause Dysfunction of Vascular Smooth Muscle CellsMuscle Cells
DAPI dihydrochloride purchased from AbMole
Adv Mater. 2023 Feb 22;e2211138.
Genetically Programmable Vesicles for Enhancing CAR-T Therapy Against Solid Tumors
DAPI dihydrochloride purchased from AbMole
Nucleic Acids Res . 2022 Aug 12;50(14):7938-7958.
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia
DAPI dihydrochloride purchased from AbMole
Oncol Lett. 2022 May;23(5):163.
AK4P1 is a cancer-promoting pseudogene in pancreatic adenocarcinoma cells whose transcripts can be transmitted by exosomes
DAPI dihydrochloride purchased from AbMole
Ann Biomed Eng. 2021 Jun;49(6):1551-1560.
Comparison of in Vascular Bioreactors and In Vivo Models of Degradation and Cellular Response of Mg-Zn-Mn Stents
DAPI dihydrochloride purchased from AbMole
Reprod Sci. 2021 Jun 2.
LncRNA HOXA-AS2 Activates the Notch Pathway to Promote Cervical Cancer Cell Proliferation and Migration
DAPI dihydrochloride purchased from AbMole
Theranostics. 2020 Apr 27;10(13):5671-5686.
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma
DAPI dihydrochloride purchased from AbMole
Oncology. 2020 Jul 20.
5-Fluorouracil enhances the chemosensitivity of gastric cancer to TRAIL via inhibition of the MAPK pathway
DAPI dihydrochloride purchased from AbMole
Life Sci. 2020 Sep 15;257:118021.
TRIB3 destabilizes tumor suppressor PPARα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia
DAPI dihydrochloride purchased from AbMole
Anat Rec (Hoboken). 2020 Jan 21.
Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation
DAPI dihydrochloride purchased from AbMole
Aging (Albany NY). 2020 Jun 9;12(11):11025-11041.
LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis
DAPI dihydrochloride purchased from AbMole
Molecular Weight | 350.25 |
Formula | C16H17Cl2N5 |
CAS Number | 28718-90-3 |
Solubility (25°C) | Water 5 mg/mL (Need ultrasonic) |
Storage | -20°C, protect from light, sealed |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
Related Fluorescent Dye Products |
---|
Mito Red
Mito Red is a cell membrane permeable rhodamine based dye. It localizes mitochondria, and emits red fluorescence. λex 569 nm; λem 594 nm in DMSO |
6-CFDA
6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. |
5-CFDA
5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. |
5(6)-FAM SE
5(6)-FAM SE is an amine-reactive green fluorescent dye widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine. |
5-FAM SE
5-FAM SE is a green fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.