About 21 results found for searched term "Leukotriene Receptor" (0.186 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2594 | Montelukast sodium | IL Receptor/Related |
| Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. | ||
| M3285 | Pranlukast | Leukotriene Receptor |
| ONO-1078 | ||
| Pranlukast is a selective cysteinyl leukotriene receptor antagonist. | ||
| M3548 | Zafirlukast | Leukotriene Receptor |
| ICI 204219 | ||
| Zafirlukast is a leukotriene receptor antagonist (LTRA) with IC50 of 0.6μM (IC50=7.0 µM for CYP2C9). | ||
| M7797 | FPL-55712 | Others |
| CysLT1 leukotriene receptor antagonist. | ||
| M7886 | LY255283 | Leukotriene Receptor |
| LY255283 is a competitive leukotriene B4 receptor antagonist, with an IC50 of about 100 nM. | ||
| M8116 | CP-105,696 | Leukotriene Receptor |
| CP-105,696 is an orally active, potent and selective leukotriene B4 receptor (LTB4R) antagonist (IC50 against [3H]LTB4 = 5. | ||
| M8140 | REV 5901 | Others |
| Leukotriene D4 receptor antagonist. | ||
| M8628 | Quininib | Others |
| Quininib is a cell penetrant, potent and selective cysteinyl leukotriene receptor 1 and 2 (CysLT1-2) antagonist that potently inhibits angiogenesis in a range of cell and tissue systems. | ||
| M20539 | Montelukast | IL Receptor/Related |
| MK0476 free base | ||
| Montelukast is a potent, selective and orally active cysteinyl leukotriene receptor 1 (CysLT1) antagonist with antioxidant activity for studies related to asthma and liver injury. | ||
| M20611 | MK571 | Others |
| L-660711, L660711, MK-571, MK 571 | ||
| MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist. | ||
| M27997 | Gemilukast | Leukotriene Receptor |
| ONO-6950 | ||
| Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. | ||
| M28676 | Etalocib | Leukotriene Receptor |
| LY293111; VML 295 | ||
| Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis. | ||
| M29132 | CP-195543 | Leukotriene Receptor |
| CP-195543 is a potent, selective and orally active leukotriene B4 (LTB4) receptor antagonist with IC50s of 6.8, 37.0 nM for human neutrophils and murine spleen membranes, respectively. CP-195543 blocks CD11b up-regulation. CP-195543 inhibits LTB4-mediated neutrophil infiltration. | ||
| M40988 | Tipelukast | Leukotriene Receptor |
| KCA 757; MN 001 | ||
| Tipelukast is an orally bioavailable leukotriene receptor antagonist with anti-inflammatory activity for studies related to asthma and non-alcoholic steatohepatitis (NASH). | ||
| M56307 | CP-96021 | Platelet-activating Factor Receptor |
| CP-96021 is a potent and orally available leukotriene D4 (LTD4 Ki=34 μM) / platelet activating factor (PAF Ki=37 μM) receptor antagonist. | ||
| M56236 | Ablukast | Leukotriene Receptor |
| Ablukast (Ro 23-3544) is a specific and active leukotriene receptor antagonist. | ||
| M56235 | BIIL-260 | Leukotriene Receptor |
| BIIL-260 is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. | ||
| M56232 | FPL-55712 free base | Leukotriene Receptor |
| FPL-55712 free base is a leukotriene receptor antagonist. | ||
| M56231 | BIIL-260 hydrochloride | Leukotriene Receptor |
| BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. | ||
| M56230 | CP-96021 hydrochloride | Leukotriene Receptor |
| CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively. | ||
| M56229 | γ-Linolenic acid ethyl ester | Leukotriene Receptor |
| γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist. | ||
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